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Proximal tibial extra-axial chordoma masquerading as renal cell carcinoma metastasis

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Abstract

Chordomas are rare, locally aggressive notochordal tumors, which most frequently occur in the neuraxis. We describe the case of a 74-year-old male with a history of renal cell carcinoma, who presented with a slowly enlarging mass in his left leg. While the clinical history and imaging suggested metastatic renal cell carcinoma, immunohistochemical staining with brachyury ultimately made the diagnosis of extra-axial chordoma. At 74 years of age, our patient is the oldest ever reported with bony extra-axial chordoma objectively confirmed by brachyury staining. A detailed case discussion and a review of the available literature on this rare clinicopathologic entity are provided.

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Authors and Affiliations

  1. Department of Radiology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA

    Jennifer Huang, Nicholas Bhojwani & Martin I. Jordanov

  2. Department of Pathology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA

    Fredrick D. Oakley

Authors
  1. Jennifer Huang
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  2. Nicholas Bhojwani
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  3. Fredrick D. Oakley
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  4. Martin I. Jordanov
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Correspondence to Jennifer Huang.

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The authors declare that they have no conflict of interest.

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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Huang, J., Bhojwani, N., Oakley, F.D. et al. Proximal tibial extra-axial chordoma masquerading as renal cell carcinoma metastasis. Skeletal Radiol 46, 1567–1573 (2017). https://doi.org/10.1007/s00256-017-2711-9

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  • DOI: https://doi.org/10.1007/s00256-017-2711-9

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