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Osteomesopyknosis—a benign axial hyperostosis that can mimic metastatic disease

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Abstract

We report two cases of an axial osteosclerosis with histopathologic findings of osteomesopyknosis in siblings. Osteomesopyknosis is a benign hereditary osteosclerosis that can show a radiologic pattern similar to blastic metastatic disease. The aim of this article is to inform radiologists about the existence of this benign condition and its various radiologic manifestations. Therefore, we discuss the principal differential diagnosis and point out the key imaging findings of osteomesopyknosis in order to avoid overdiagnosis in future cases.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Radiology Department of the University Hospital, Hospital Universitario Puerta del Mar, Cádiz, Spain

    Eva-Marie Heursen, María del Carmen González Partida, José Paz Expósito & Federico Navarro Díaz

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  1. Eva-Marie Heursen
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  2. María del Carmen González Partida
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  3. José Paz Expósito
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  4. Federico Navarro Díaz
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Correspondence to Eva-Marie Heursen.

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Heursen, EM., González Partida, M.d., Paz Expósito, J. et al. Osteomesopyknosis—a benign axial hyperostosis that can mimic metastatic disease. Skeletal Radiol 45, 141–146 (2016). https://doi.org/10.1007/s00256-015-2216-3

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  • DOI: https://doi.org/10.1007/s00256-015-2216-3

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