Abstract
We report the case of an 11-year-old boy who came to our observation with localized pain in the left arm for nearly 5 months. No previous history of trauma was referred in an otherwise healthy patient. Radiographs, isotope bone-scan, computed tomography, and magnetic resonance imaging of the lesion involving the left humerus are discussed. Histological diagnosis from biopsy of the humerus was metastasis from mucinous adenocarcinoma. The primary tumor site was identified in the sigmoid-descending colon, and at presentation, in addition to the left humerus, the disease had already developed in multiple skeletal sites. This report also considers literature concerning such a rare disease in children. This is, to our knowledge, the first report of childhood colorectal cancer diagnosed because of a bone metastasis.
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Acknowledgments
The authors thank Gambarotti Marco, MD, Surgical Pathology of the Rizzoli Orthopaedic Institute for his help in description of histological features of the case. The authors also thank Balladelli Alba, BA (Laboratory of Experimental Oncology, Rizzoli Orthopaedic Institute, Bologna, Italy) for her precious help in the editing process. The authors thank Paolucci Paolo, PhD (Pediatrics Unit, Department of Mother & Child, University Hospital of Modena, Italy) for accurate information about chemotherapy treatment and clinical course of the patient.
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Colangeli, M., Calamelli, C., Manfrini, M. et al. Bone metastasis from colon carcinoma in an 11-year-old boy: radiological features and brief review of the literature. Skeletal Radiol 44, 743–748 (2015). https://doi.org/10.1007/s00256-014-2039-7
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DOI: https://doi.org/10.1007/s00256-014-2039-7