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Diffuse bone marrow sarcoid-like reaction associated with renal cell carcinoma

Skeletal Radiology volume 43, pages 1761–1766 (2014)Cite this article

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Abstract

Sarcoid-like reaction has been documented in association with several types of malignancy, including renal cell carcinoma. We report the case of a 41-year-old man with nonmetastatic renal cell carcinoma and concomitant non-caseating granulomas distributed diffusely throughout the bone marrow. The granulomas resolved after nephrectomy. As far as we know, this is the first reported case of a sarcoid-like reaction primarily involving the bone marrow in association with renal cell carcinoma.

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Acknowledgments

Special thanks to Vighnesh Walavalkar, MD, for his assistance in interpreting the pathologic data and for providing the pathologic slides.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA, 01655, USA

    Timothy F. Madden & Steven J. Baccei

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  1. Timothy F. Madden
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  2. Steven J. Baccei
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Correspondence to Timothy F. Madden.

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Madden, T.F., Baccei, S.J. Diffuse bone marrow sarcoid-like reaction associated with renal cell carcinoma. Skeletal Radiol 43, 1761–1766 (2014). https://doi.org/10.1007/s00256-014-1960-0

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  • DOI: https://doi.org/10.1007/s00256-014-1960-0

Keywords

  • Sarcoid
  • Sarcoid like
  • Renal cell carcinoma
  • Granuloma