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Human hand radiography using X-ray differential phase contrast combined with dark-field imaging

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References

  1. David C, Nöhammer B, Solak H, Ziegler E. Differential x-ray phase contrast imaging using a shearing interferometer. Appl Phys Lett. 2002;81(17):3287–9.

    Article  CAS  Google Scholar 

  2. Pfeiffer F, Weitkamp T, Bunk O, David C. Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources. Nat Phys. 2006;2(4):258–61.

    Article  CAS  Google Scholar 

  3. Engelhardt M, Baumann J, Schuster M, Kottler C, Pfeiffer F, Bunk O, et al. High-resolution differential phase contrast imaging using a magnifying projection geometry with a microfocus x-ray source. Appl Phys Lett. 2007;90(22):224101.

    Article  Google Scholar 

  4. Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry E, Brönnimann C, et al. Hard-X-ray dark-field imaging using a grating interferometer. Nat Mater. 2008;7(2):134–7.

    Article  PubMed  CAS  Google Scholar 

  5. Engel KKJK, Geller D, Köhler T, Martens G, Schusser S, Vogtmeier G, et al. Contrast-to-noise in X-ray differential phase contrast imaging. Nucl Inst Methods Phys Res A. 2010;648:202–7.

    Article  Google Scholar 

  6. Stampanoni M, Wang Z, Thüring T, David C, Roessl E, Trippel M, et al. The first analysis and clinical evaluation of native breast tissue using differential phase-contrast mammography. Investig Radiol. 2011;46(12):801–6.

    Article  CAS  Google Scholar 

  7. Steinbach L, Resnick D. Calcium pyrophosphate dihydrate crystal deposition disease: imaging perspectives. Curr Probl Diagn Radiol. 2000;29(6):209–29.

    Article  PubMed  CAS  Google Scholar 

  8. Koutaissoff S, Vanthuyne M, Smith V, De Langhe E, Depresseux G, Westhovens R, et al. Hand radiological damage in systemic sclerosis: comparison with a control group and clinical and functional correlations. Semin Arthritis Rheum. 2011;40(5):455–60.

    Article  PubMed  Google Scholar 

  9. Coan P, Bamberg F, Diemoz P, Bravin A, Timpert K, Mützel E, et al. Characterization of osteoarthritic and normal human patella cartilage by computed tomography X-ray phase-contrast imaging: a feasibility study. Investig Radiol. 2010;45(7):437–44.

    Google Scholar 

  10. Stutman D, Beck TJ, Carrino JA, Bingham CO. Talbot phase-contrast x-ray imaging for the small joints of the hand. Phys Med Biol. 2011;56(17):5697–720.

    Article  PubMed  Google Scholar 

  11. Donath T, Pfeiffer F, Bunk O, Grünzweig C, Hempel E, Popescu S, et al. Toward clinical X-ray phase-contrast CT: demonstration of enhanced soft-tissue contrast in human specimen. Investig Radiol. 2010;45(7):445–52.

    Google Scholar 

  12. Jensen T, Bech M, Zanette I, Weitkamp T, David C, Deyhle H, et al. Directional x-ray dark-field imaging of strongly ordered systems. Phys Rev B. 2010;82(21):214103.

    Article  Google Scholar 

  13. Kottler C, David C, Pfeiffer F, Bunk O. A two-directional approach for grating based differential phase contrast imaging using hard x-rays. Opt Express. 2007;15(3):1175–81.

    Article  PubMed  CAS  Google Scholar 

  14. Thiel W. Die Konservierung ganzer Leichen in natürlichen Farben. Ann Anat Anat Anzeiger. 1992;174(3):185–95.

    Article  CAS  Google Scholar 

  15. David C, Bruder J, Rohbeck T, Grünzweig C, Kottler C, Diaz A, Fabrication of diffraction gratings for hard X-ray phase contrast imaging. Microelectron Eng. 2007;84(5–8):1172–1177.

    Article  CAS  Google Scholar 

  16. Kenntner J, Grund T, Matthis B, Boerner M, Mohr J, Scherer T et al. Front- and backside structuring of gratings for phase contrast imaging with x-ray tubes. Proc SPIE. 2010. 10.1117/12.859666

    Google Scholar 

  17. Zanette I, Weitkamp T, Donath T, Rutishauser S, David C. Two-dimensional X-Ray grating interferometer. Phys Rev Lett. 2010;105:248102.

    Article  PubMed  Google Scholar 

  18. Van der Heide D. How to read radiographs according to the Sharp/van der Heijde method. J Rheumatol. 2000;27(1):261–3.

    Google Scholar 

  19. Kellgren J, Lawrence J. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16(4):494–502.

    Article  PubMed  CAS  Google Scholar 

  20. Weitkamp T, Diaz A, David C, Pfeiffer F, Stampanoni M, Cloetens P, et al. X-ray phase imaging with a grating interferometer. Opt Express. 2005;12(16):6296–304.

    Article  Google Scholar 

  21. Fouque-Aubert A, Boutroy S, Marotte H, Vilayphiou N, Lespessailles E, Benhamou C, et al. Assessment of hand trabecular bone texture with high resolution direct digital radiograph in rheumatoid arthritis: a case control study. Joint Bone Spine. 2012;79(4):379–83.

    Article  PubMed  Google Scholar 

  22. Pye S, Adams J, Ward K, Brunn D, Symmons D, O'Neill T. Disease activity and severity in early inflammatory arthritis predict hand cortical bone loss. Rheumatology. 2010;49(10):1943–8.

    Article  PubMed  Google Scholar 

  23. Aletaha D, Neogi T, Silman A, Funovits J, Felson D, Bingham C, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62(9):2569–81.

    Article  PubMed  Google Scholar 

  24. Spector T, Cooper C. Radiographic assessment of osteoarthritis in population studies: whither Kellgren and Lawrence? Osteoarthr Cartil. 1993;1:203–6.

    Article  PubMed  CAS  Google Scholar 

  25. Altman RD, Gold GE. Atlas of individual radiographic features in osteoarthritis, revised. Osteoarthr Cartil. 2007;15:A1–A56.

    Article  PubMed  Google Scholar 

  26. Thuering T, Modregger P, Grund T, Kenntner J, David C, Stampanoni M. High resolution, large field of view x-ray differential phase contrast imaging on a compact setup. Appl Phys Lett. 2011;99(4):041111.

    Article  Google Scholar 

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Acknowledgements

The authors thank Gordan Mikuljan from Paul Scherrer Institute for the design and manufacturing of various mechanical components. They also thank Prof. Verdun from the Institute of Radiation Physics at the University Hospital center Lausanne for his competent help in dose calculations. Part of this work has been supported by the ERC Grant ERC-2012-StG 310005-PhaseX.

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Authors and Affiliations

  1. Paul Scherrer Institut, WBBA/213, 5232, Villigen, Switzerland

    Thomas Thüring, Zhentian Wang, Christian David & Marco Stampanoni

  2. Institute for Biomedical Engineering, Swiss Federal Institute of Technology, Zurich, Switzerland

    Thomas Thüring & Marco Stampanoni

  3. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland

    Roman Guggenberger, Hatem Alkadhi & Jürg Hodler

  4. Institute of Anatomy, University Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland

    Magdalena Vich

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  1. Thomas Thüring
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  7. Christian David
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  8. Marco Stampanoni
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Correspondence to Thomas Thüring.

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Thüring, T., Guggenberger, R., Alkadhi, H. et al. Human hand radiography using X-ray differential phase contrast combined with dark-field imaging. Skeletal Radiol 42, 827–835 (2013). https://doi.org/10.1007/s00256-013-1606-7

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  • DOI: https://doi.org/10.1007/s00256-013-1606-7

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