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The use of FDG-PET/CT in extranodal Rosai–Dorfman disease of bone

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Abstract

We report the case of a 41-year-old man with extranodal Rosai–Dorfman disease (RDD), presenting with clinically detectable bone involvement only. The use of FDG-PET/CT in the diagnosis of RDD is discussed.

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References

  1. Foucar E, Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease): review of the entity. Semin Diagn Pathol. 1990;7:19–73.

    PubMed  CAS  Google Scholar 

  2. Walker PD, Rosai J, Dorfman RF. The osseous manifestations of sinus histiocytosis with massive lymphadenopathy. Am J Clin Pathol. 1981;75:131–9.

    PubMed  CAS  Google Scholar 

  3. Abdelwahab IF, Klein MJ, Springfield DS, Hermann G. A solitary lesion of talus with mixed sclerotic and lytic changes: Rosai–Dorfman disease of 25 years' duration. Skeletal Radiol. 2004;33:230–3.

    Article  PubMed  Google Scholar 

  4. Gupta S, Finzel KC, Grubber BL. Rosai–Dorfman disease masquerading as chronic ankle arthritis: a case report and review of the literature. Rheumatology (Oxford). 2004;43:811–2.

    Article  CAS  Google Scholar 

  5. Demicco EG, Rosenberg AE, Björnsson J, Rybak LD, Unni KK, Nielsen GP. Primary Rosai–Dorfman disease of bone: a clinicopathologic study of 15 cases. Am J Surg Pathol. 2010;34:1324–33.

    Article  PubMed  Google Scholar 

  6. Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy: a pseudolymphomatous benign disorder. Analysis of 34 cases. Cancer. 1972;30:1174–88.

    Article  PubMed  CAS  Google Scholar 

  7. Menzel C, Hamscho N, Döbert N, et al. PET imaging of Rosai–Dorfman disease: correlation with histopathology and ex-vivo beta-imaging. Arch Dermatol Res. 2003;295:280–3.

    Article  PubMed  Google Scholar 

  8. Lim R, Wittram C, Ferry JA, Shepard JA. FDG PET of Rosai–Dorfman disease of the thymus. AJR Am J Roentgenol. 2004;182:514.

    PubMed  Google Scholar 

  9. Yu JQ, Zhuang H, Xiu Y, Talati E, Alavi A. Demonstration of increased FDG activity in Rosai–Dorfman disease on positron emission tomography. Clin Nucl Med. 2004;29:209–10.

    Article  PubMed  Google Scholar 

  10. Konca C, Ozkurt ZN, Deger M, Aki Z, Yağci M. Extranodal multifocal Rosai–Dorfman disease: response to 2-chlorodeoxyadenosine treatment. Int J Hematol. 2009;89:58–62.

    Article  PubMed  Google Scholar 

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The authors declare that they have no conflicts of interest.

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Correspondence to Marina-Portia Anthony.

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Tsang, J.S., Anthony, MP., Wong, M.P. et al. The use of FDG-PET/CT in extranodal Rosai–Dorfman disease of bone. Skeletal Radiol 41, 715–717 (2012). https://doi.org/10.1007/s00256-012-1382-9

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  • DOI: https://doi.org/10.1007/s00256-012-1382-9

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