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Benign notochordal lesions of the axial skeleton: a review and current appraisal

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Abstract

At the 1996 meeting of the International Skeletal Society, an idea was put forth that there existed symptomatic lesions of the axial skeleton, morphologically different from chordoma, that were consistent with benign notochordal remnants (rests). A review of the embryological basis for this concept is made, along with an analysis of these lesions, termed giant notochordal rests or benign notochordal cell tumors, that have been reported in the intervening 15 years, with a commentary on their relationship, if any, to chordoma.

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Notes

  1. Some of the following data include additional clinical information obtained in personal communication from Drs. Dorfman [45], McCarthy [37], and Reith [47] on their patients.

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Acknowledgement

The author gratefully acknowledges Dr. Murali Sundaram for his helpful suggestions in the preparation of this manuscript.

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  1. Division of Surgical Pathology, Washington University School of Medicine, Box 8118, St. Louis, MO, USA

    Michael Kyriakos

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Correspondence to Michael Kyriakos.

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Portions of this article were discussed at the International Academy of Pathology Meetings in Montreal in 2006 and Athens in 2008

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Kyriakos, M. Benign notochordal lesions of the axial skeleton: a review and current appraisal. Skeletal Radiol 40, 1141–1152 (2011). https://doi.org/10.1007/s00256-011-1167-6

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