Skip to main content

Advertisement

Log in

Simultaneous thigh muscle metastasis from lung cancer and Escherichia coli gas producing myonecrosis

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

We present the case of a 41-year-old man with known large cell lung cancer who had undergone left pneumonectomy 7 months prior and who presented with a large intramuscular mass involving the posterior left thigh and upper calf. This thigh mass was ultimately surgically explored, and specimens yielded both Escherichia coli organisms and cells reflecting a skeletal muscle metastasis from the patient’s known lung cancer. The patient was also found to have a rectal metastasis from his lung cancer. Intramuscular abscesses produced by gastrointestinal tract flora are a well-known presentation of colon cancer. To our knowledge, this is the first case report of the simultaneous occurrence of a skeletal muscle metastasis and an E. coli abscess in the same anatomic location. We believe the patient’s rectal metastasis may have been the intermediate step in this process.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Mzabi R, Himal HS, MacLean LD. Gas gangrene of the extremity: the presenting clinical picture in perforating carcinoma of the caecum. Br J Surg 1975; 62: 373–374.

    Article  CAS  Google Scholar 

  2. Gazzaniga A. Nontraumatic, clostridial, gas gangrene of the right arm and adenocarcinoma of the cecum: report of a case. Dis Colon Rectum 1966; 10: 298–300.

    Article  Google Scholar 

  3. Valentine J. Gas gangrene septicemia due to carcinoma of the caecum and muscular trauma. Br J Surg 1957; 44: 630–632.

    Article  CAS  Google Scholar 

  4. Schaaf RE, Jacobs N, Kelvi FM, Gallis HA, Akwari O, Thompson WM. Clostridium septicum infection associated with colonic carcinoma and hematologic abnormality. Radiology 1980; 137: 625–627.

    Article  CAS  Google Scholar 

  5. Furste W, Dolor MC, Rothstein LB, Vest GR. Carcinoma of the large intestine and nontraumatic, metastatic clostridial myonecrosis. Dis Colon Rectum 1986; 29: 899–904.

    Article  CAS  Google Scholar 

  6. Nicell P, Tabrisky J, Lindstrom R, Peter M. Thigh emphysema and hip pain secondary to gastrointestinal perforation. Surgery 1975; 78: 555–559.

    CAS  PubMed  Google Scholar 

  7. Robbins PL, Sutherland DER, Najarian JS, Bernstein WC. Emphysema of the leg as a presenting sign of large intestinal perforation: report of two cases. Dis Col Rect 1977; 20: 144–148.

    Article  CAS  Google Scholar 

  8. Fox TA, Gomez J, Bravo J. Subcutaneous emphysema of the lower extremity of gastrointestinal origin. Dis Colon Rectum 1978; 21: 357–360.

    Article  Google Scholar 

  9. Yoshimoto A, Kasahara K, Kawashima A. Gastrointestinal metastases from primary lung cancer. Eur J Cancer 2006; 42: 3157–3160.

    Article  Google Scholar 

  10. Burbige EJ, Radigan JJ, Belber JP. Metastatic lung carcinoma involving the gastrointestinal tract. Am J Gastroenterol 1980; 74: 504–506.

    CAS  PubMed  Google Scholar 

  11. Antler AS, Ough Y, Pitchumoni S, Davidian M, Thelmo W. Gastrointestinal metastases from malignant tumors of the lung. Cancer 1982; 49: 170–172.

    Article  CAS  Google Scholar 

  12. Stenbygaard LE, Sorenson JB, Larsen H, Dombernowsky P. Metastatic pattern in non-resectable non-small cell lung cancer. Acta Oncol 1999; 38: 993–998.

    Article  CAS  Google Scholar 

  13. Elliott JA, Osterlind K, Hirsch FR, Hansen HH. Metastatic patterns in small-cell lung cancer: correlation of autopsy findings with clinical parameters in 537 patients. J Clin Oncol 1987; 5: 246–254.

    Article  CAS  Google Scholar 

  14. Stenbygaard LE, Sorensen JB, Olsen JE. Metastatic pattern of adenocarcinoma of the lung: an autopsy study from a cohort of 137 consecutive patients with complete resection. J Thorac Cardiovasc Surg 1995; 110: 1130–1135.

    Article  CAS  Google Scholar 

  15. Washington K, McDonagh D. Secondary tumors of the gastrointestinal tract: surgical pathologic findings and comparison with autopsy survey. Mod Pathol 1995; 8: 427–433.

    CAS  PubMed  Google Scholar 

  16. Damron TA, Heiner J. Distant soft tissue metastases: a series of 30 new patients and 91 cases from the literature. Ann Surg Oncol 2000; 7: 526–534.

    Article  CAS  Google Scholar 

  17. Schultz SR, Bree RL, Schwab RE, Raiss G. CT detection of skeletal muscle metastases. J Comput Assist Tomogr 1986; 10: 81–83.

    Article  CAS  Google Scholar 

  18. Pretorius ES, Fishman EK. Helical CT of skeletal muscle metastases from primary carcinomas. AJR Am J Roentgenol 2000; 174: 401–404.

    Article  CAS  Google Scholar 

  19. Suto Y, Yamaguchi Y, Sugihara S. Skeletal muscle metastasis from lung carcinoma: MR findings. J Comput Assist Tomogr 1997; 21: 304–305.

    Article  CAS  Google Scholar 

  20. Gordon BA, Martinez S, Collins AJ. Pyomyositis: characteristics at CT and MR imaging. Radiology 1995; 197: 279–286.

    Article  CAS  Google Scholar 

  21. Bickels J, Ben-Sira L, Kessler A, Wientroub S. Primary pyomyositis. J Bone Joint Surg Am 2002; 84: 2277–2286.

    Article  CAS  Google Scholar 

  22. Chiedozi L. Pyomyositis: review of 205 cases in 112 patients. Am J Surg 1979; 137: 255–259.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Salutario Martinez.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Martinez, G.E., Coursey, C.A., Dodd, L. et al. Simultaneous thigh muscle metastasis from lung cancer and Escherichia coli gas producing myonecrosis. Skeletal Radiol 37, 763–766 (2008). https://doi.org/10.1007/s00256-008-0489-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-008-0489-5

Keywords

Navigation