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Congenital osteofibrous dysplasia associated with pseudoarthrosis of the tibia and fibula

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Abstract

The association between congenital pseudoarthrosis and osteofibrous dysplasia of the tibia and fibula is a rare entity that has been recently recognized. We report a male newborn who was found to have swelling and deformity of the left lower leg. Radiographs and magnetic resonance imaging showed an extensive destructive lesion of the tibial shaft, with dysplastic congenital pseudoarthrosis of the lower fibula. Histopathologial examination confirmed the diagnosis of congenital pseudoarthrosis of the tibia and fibula with underlying osteofibrous dysplasia involving both bones. Immunohistochemical stains showed cytokeratin positivity.

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Authors and Affiliations

  1. Department of Diagnostic Imaging, KK Women’s and Children’s Hospital, 100 Bukit Timah Road, 229899, Singapore

    Harvey E. L. Teo & Wilfred C. G. Peh

  2. Department of Pathology, KK Women’s and Children’s Hospital, 100 Bukit Timah Road, Singapore

    M. Akhilesh

  3. Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore

    S. B. Tan

  4. Department of Pathology, Kanto Medical Center, Tokyo, Japan

    T. Ishida

Authors
  1. Harvey E. L. Teo
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  2. Wilfred C. G. Peh
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  3. M. Akhilesh
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  4. S. B. Tan
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  5. T. Ishida
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Corresponding author

Correspondence to Wilfred C. G. Peh.

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Teo, H.E.L., Peh, W.C.G., Akhilesh, M. et al. Congenital osteofibrous dysplasia associated with pseudoarthrosis of the tibia and fibula. Skeletal Radiol 36 (Suppl 1), 7–14 (2007). https://doi.org/10.1007/s00256-006-0177-2

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  • DOI: https://doi.org/10.1007/s00256-006-0177-2

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