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Tophaceous gout in the cervical spine

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Abstract

Gout is a common metabolic disorder typically affecting the distal joints of the appendicular skeleton. Involvement of the axial skeleton, particularly the facet joints and posterior column of the cervical spine, is rare. This case report highlights such a presentation in a 76-year old female who presented with cervical spine pain following a fall. Her radiological findings were suggestive of a destructive metastatic process. Histological diagnosis confirmed tophaceous gout.

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References

  1. Kim K, Schumacher H, Hunsche E, et al. A literature review of the epidemiology and treatment of acute gout. Clin Ther 2003; 25(6):1593–617

    Google Scholar 

  2. Terkeltaub R. Gout. N Engl J Med 2003; 349:1647–1655.

    Article  PubMed  CAS  Google Scholar 

  3. Cotran R, Kumar V, Collins T. Robbins pathologic basis of disease, 6th edn. Philadelphia: WB Saunders, 1999.

  4. Duprez T, Malghem J, Vande Berg B, et al. Gout in the cervical spine: MR pattern mimicking discovertebral infection. Am J Neuroradiol 1996; 17(1):151–153.

    Google Scholar 

  5. Vinstein A, Cockerill E. Involvement of the spine in gout. Radiology 1972; 103(2): 311–312.

    Google Scholar 

  6. Diaz A, Porhiel V, Sabatier P, et al. Tophaceous gout of the cervical spine, causing cord compression. Case report and review of literature. Neurochirurgie 2003; 49(6):600–604.

    Google Scholar 

  7. Alarcon G, Reveille J. Gouty arthritis of the axial skeleton including the sacroiliac joints. Arch Intern Med 1987; 147(11):2018–2019.

    Google Scholar 

  8. Magid S, Gray G, Amand A. Spinal cord compression by tophi in patient with chronic polyarthritis. Arthritis Rheum 1981; 24:1431–1434.

    Article  PubMed  CAS  Google Scholar 

  9. Lichtenstein L, Scott H, Levin M. Pathologic changes in gout: survey of eleven necropsied cases. Am J Pathol 1956; 32:871–895.

    PubMed  Google Scholar 

  10. Hall M, Selin G. Spinal involvement in gout. J Bone Joint Surg 1960;42:341–343.

    Google Scholar 

  11. Tkach S. Gouty arthritis of the spine. Clin Orthop 1970; 71:81–86.

    PubMed  CAS  Google Scholar 

  12. Resnick, D. Gouty Arthritis. In: Resnick D, ed. Diagnosis of bone and joint disorders, 4th edn. Philadelphia: Saunders, 2002:1519–1560.

  13. Alcalay M, Goupy M, Azais I, Bontoux D. Hemodialysis is not essential for the development of destructive spondylarthropathy in patients with chronic renal failure. Arthritis Rheum 1987; 30(10):1182–1186.

    Google Scholar 

  14. Aaron S, Miller J, Percy J. Tophaceous gout in the cervical spine. J Rheumatol 1984; 11(6):862–865.

    Google Scholar 

  15. Snaith M. ABC of Rheumatology: gout, hyperuricaemia and crystal arthritis. BMJ 1995; 310:521–524.

    PubMed  CAS  Google Scholar 

  16. Emmerson B. The management of gout. N Engl J Med 1996; 334:445–451.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgements

The authors would like to thank Mr. A. Szabo and Dr. L. Henry (Gribbles Pathology).

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Correspondence to Leigh Mosel.

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Cabot, J., Mosel, L., Kong, A. et al. Tophaceous gout in the cervical spine. Skeletal Radiol 34, 803–806 (2005). https://doi.org/10.1007/s00256-005-0920-0

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  • DOI: https://doi.org/10.1007/s00256-005-0920-0

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