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Isolated lower extremity metastases, 9 years after initial diagnosis of retinoblastoma

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Abstract

We report the development of isolated lower extremity metastases, in a child, 9 years after her initial diagnosis and treatment of bilateral infantile retinoblastomas. The radiographic, scintigraphic, computed tomographic, and magnetic resonance imaging findings are discussed. The dominant metastatic focus was blastic, involving the medial cuneiform. Additional occult lesions were found in the base of the second metatarsal, middle cuneiform, navicular and tibial diaphysis. An open biopsy confirmed the diagnosis. The occurrence of late distant metastases is rare in the USA.

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Authors and Affiliations

  1. Department of Radiology, Medical School, University of Maryland, 22 South Greene Street, Baltimore, MD , 21201, USA

    M. E. Mulligan & S. E. Smith

  2. Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, 21205, USA

    E. F. McCarthy Jr.

Authors
  1. M. E. Mulligan
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  2. S. E. Smith
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  3. E. F. McCarthy Jr.
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Corresponding author

Correspondence to M. E. Mulligan.

Additional information

This case was presented at the 31st Annual Closed Members Meeting of the International Skeletal Society held in Malta, October 2004.

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Mulligan, M.E., Smith, S.E. & McCarthy, E.F. Isolated lower extremity metastases, 9 years after initial diagnosis of retinoblastoma. Skeletal Radiol 35, 774–777 (2006). https://doi.org/10.1007/s00256-005-0916-9

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  • DOI: https://doi.org/10.1007/s00256-005-0916-9

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