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Hyperplastic callus formation in osteogenesis imperfecta type V mimicking osteosarcoma: 4-year follow-up with resolution

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Abstract

We report a case of hyperplastic callus formation that occurred in both femurs in a patient with type V osteogenesis imperfecta (OI), with 4-year follow-up and resolution. The clinical, histological and imaging aspects of this condition are discussed. Recognition of the hyperplastic callus formation in this particular type of OI is important in order to avoid misdiagnosis.

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References

  1. Hanscom DA, Winter RB, Lutter L, Lonstein JE, Bloom BA, Bradford DS. (1992) Osteogenesis imperfecta. Radiographic classification, natural history, and treatment of spinal deformities. J Bone Joint Surg Am 74(4):598–616

    Article  CAS  Google Scholar 

  2. Kutsumi K, Nojima T, Yamashiro K, Hatae Y, Isu K, Ubayama Y, et al. (1996) Hyperplastic callus formation in both femurs in osteogenesis imperfecta. Skelet Radiol 25(4):384–387

    Article  CAS  Google Scholar 

  3. Glorieux FH, Rauch F, Plotkin H, Ward L, Travers R, Roughley P, et al. (2000) Type V osteogenesis imperfecta: a new form of brittle bone disease. J Bone Miner Res 15(9):1650–1658

    Article  CAS  Google Scholar 

  4. Smith R. (2001) Hyperplastic callus and osteogenesis imperfecta. Lancet 357(9252):248–249

    Article  CAS  Google Scholar 

  5. Sillence D. (1981) Osteogenesis imperfecta: an expanding panorama of variants. Clin Orthop Relat Res (159):11–25

  6. Zeitlin L, Fassier F, Glorieux FH. (2003) Modern approach to children with osteogenesis imperfecta. J Pediatr Orthop B 12(2):77–87

    PubMed  Google Scholar 

  7. Banta JV, Schreiber RR, Kulik WJ. (1971) Hyperplastic callus formation in osteogenesis imperfecta simulating osteosarcoma. J Bone Joint Surg Am 53(1):115–122

    Article  CAS  Google Scholar 

  8. Burchardt AJ, Wagner AA, Basse P. (1994) Hyperplastic callus formation in osteogenesis imperfecta. A case report. Acta Radiol 35(5):426–428

    Article  CAS  Google Scholar 

  9. Yekeler E, Kumbasar B, Dursun M, Cantez S, Emiroglu HH, Tunaci M. (2003) Pseudomass of the sternal manubrium in osteogenesis imperfecta. Skelet Radiol 32(6):371–373

    Article  Google Scholar 

  10. McCall RE, Bax JA. (1984) Hyperplastic callus formation in osteogenesis imperfecta following intramedullary rodding. J Pediatr Orthop 4(3):361–364

    Article  CAS  Google Scholar 

  11. Maiya S, Grimer RJ, Ramaswamy R, Deshmukh NS. (2002) Osteosarcoma occurring in osteogenesis imperfecta tarda. Int Orthop 26(2):126–128

    Article  CAS  Google Scholar 

  12. Takahashi S, Okada K, Nagasawa H, Shimada Y, Sakamoto H, Itoi E. (2004) Osteosarcoma occurring in osteogenesis imperfecta. Virchows Arch 444(5):454–458

    Article  Google Scholar 

  13. Rieker O, Kreitner KF, Karbowski A. (1998) Hyperplastic callus formation in osteogenesis imperfecta: CT and MRI findings. Eur Radiol 8(7):1137–1139

    Article  CAS  Google Scholar 

  14. Azouz EM, Fassier F. (1997) Hyperplastic callus formation in OI. Skelet Radiol 26(12):744–745

    Article  CAS  Google Scholar 

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Acknowledgements

We thank Dr. Maria do Carmo Guedes Alcoforado Assunção for the pathology analysis. We also thank Dr. Rodrigo Yacubian Fernandes, Dr. Marise Lazaretti Castro, Dr. Laura Duarte Lessa and Dr. Gilberto Vieira for their contributions.

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Authors and Affiliations

  1. Department of Radiology, Federal University of Sao Paulo, Sao Paulo, Brazil

    R. L. V. Vieira, D. T. Amaral & A. R. C. Fernandes

  2. Department of Orthopedic Surgery, Federal University of Sao Paulo, Sao Paulo, Brazil

    Filho R. Jesus-Garcia

  3. Department of Endocrinology, Federal University of Sao Paulo, Sao Paulo, Brazil

    G. Saraiva

  4. Rua Botucatu 740 – DDI – Vila Mariana, São Paulo, SP, 04023–062, Brazil

    A. R. C. Fernandes

  5. Department of MSK Radiology, University of California San Diego, San Diego, CA, USA

    D. Resnick

Authors
  1. R. L. V. Vieira
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  2. D. T. Amaral
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  3. Filho R. Jesus-Garcia
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  4. G. Saraiva
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  5. A. R. C. Fernandes
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  6. D. Resnick
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Corresponding author

Correspondence to A. R. C. Fernandes.

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Vieira, R.L.V., Amaral, D.T., Jesus-Garcia, F.R. et al. Hyperplastic callus formation in osteogenesis imperfecta type V mimicking osteosarcoma: 4-year follow-up with resolution. Skeletal Radiol 35, 402–405 (2006). https://doi.org/10.1007/s00256-005-0039-3

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  • DOI: https://doi.org/10.1007/s00256-005-0039-3

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