Skip to main content

Advertisement

Log in

Sclerosing perineurioma: tumor of the hand with a short T2

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

We present two cases of sclerosing perineurioma, a rare soft tissue tumor, in the palm and the ring finger respectively, presenting as a small, painless and subcutaneous mass. This tumor has a predilection for the digits and palms of young, predominantly male adults. In the present cases the tumors showed very low signal intensity on T2-weighted magnetic resonance (MR) images. Histologically they contained abundant collagen and hyalinized stroma, which would account for areas of low signal intensity on T2-weighted MR images. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen and human erythrocyte glucose transporter 1 and negative for S-100 protein. To the best of our knowledge, the appearance of sclerosing perineurioma on MR imaging has not been previously reported in the English-language literature. Sclerosing perineurioma should be considered in the differential diagnosis of hand tumors when the tumor shows low signal intensity on T2-weighted MR images.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Lazarus SS, Trombetta LD. Ultrastructural identification of a benign perineurial cell tumor. Cancer 1978;41:1823–9

    Article  PubMed  CAS  Google Scholar 

  2. Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997;21:1433–42

    Article  PubMed  CAS  Google Scholar 

  3. Yamaguchi U, Hasegawa T, Hirose T, et al. Sclerosing perineurioma: a clinicopathological study of five cases and diagnostic utility of immunohistochemical staining for GLUT1. Virchows Arch 2003;443:159–63

    Article  PubMed  Google Scholar 

  4. Canales-Ibarra C, Magarinos G, Olsoff-Pagovich P, Ortiz-Hidalgo C. Cutaneous sclerosing perineurioma of the digits: an uncommon soft-tissue neoplasm. Report of two cases with immunohistochemical analysis. J Cutan Pathol 2003;30:577–81

    Article  PubMed  Google Scholar 

  5. Huang HY, Sung MT. Sclerosing perineuriomas affecting bilateral hands. Br J Dermatol 2002;146:129–33

    Article  PubMed  Google Scholar 

  6. Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T. Immunohistochemical demonstration of EMA/GLUT1-positive perineurial cells and CD34 positive fibroblastic cells in peripheral nerve sheath tumors. Mod Pathol 2003;116:293–8

    Article  Google Scholar 

  7. Sundaram M, McGuire MH, Schajowicz F. Soft tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images. AJR 1987;148:1247–50

    PubMed  CAS  Google Scholar 

  8. Karasick D, Karasick S. Giant cell tumor of tendon sheath: spectrum of radiologic findings. Skelet Radiol 1992;21:219–24

    CAS  Google Scholar 

  9. Horcajadas AB, Lafuente JL, de la Cruz Burgos R, et al. Ultrasound and MR findings in tumor and tumor-like lesions of the fingers. Eur Radiol 2003;13:672–85

    PubMed  Google Scholar 

  10. Kato K, Ehara S, Nishida J, et al. Rapid involution of proliferative fasciitis. Skelet Radiol 2004;33:300–2

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ukihide Tateishi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Miyake, M., Tateishi, U., Maeda, T. et al. Sclerosing perineurioma: tumor of the hand with a short T2. Skeletal Radiol 35, 543–546 (2006). https://doi.org/10.1007/s00256-005-0037-5

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-005-0037-5

Keywords

Navigation