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Synchronous intracortical adamantinomas with keratin cyst formation

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Abstract

Adamantinoma of the long bones is a rare primary bone tumor of uncertain embryogenesis. It tends to involve the tibia almost exclusively. We report on adamantinomas occurring in a 16-year-old male patient, with synchronous tibial and fibular lesions. Histologically, there were characteristic clusters of epithelial cells in a fibrous background, forming a keratin cyst. Immunohistochemically, these cells were strongly positive for cytokeratin. This keratin cyst formation is quite an unusual finding in classic adamantinoma.

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Authors and Affiliations

  1. Department of Pathology, College of Medicine, Kyung Hee University, Seoul, South Korea

    Yong-Koo Park

  2. Department of Diagnostic Radiology, College of Medicine, Kyung Hee University, Seoul, South Korea

    Kyung Nam Ryu

  3. Department of Orthopedic Surgery, College of Medicine, Kyung Hee University, Seoul, South Korea

    Chung Soo Han

  4. Department of Pathology, Kyung Hee University Hospital, 1 Hoeki-dong, Dongdaemoon-gu, Seoul, 130-702, South Korea

    Yong-Koo Park

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  1. Yong-Koo Park
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  2. Kyung Nam Ryu
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  3. Chung Soo Han
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Correspondence to Yong-Koo Park.

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Park, YK., Ryu, K.N. & Han, C.S. Synchronous intracortical adamantinomas with keratin cyst formation. Skeletal Radiol 35, 185–189 (2006). https://doi.org/10.1007/s00256-005-0005-0

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  • DOI: https://doi.org/10.1007/s00256-005-0005-0

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