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Malignant fatty tumors: classification, clinical course, imaging appearance and treatment

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Abstract

Liposarcoma is a relatively common soft tissue malignancy with a wide spectrum of clinical presentations and imaging appearances. Several subtypes are described, ranging from lesions nearly entirely composed of mature adipose tissue, to tumors with very sparse adipose elements. The imaging appearance of these fatty masses is frequently sufficiently characteristic to allow a specific diagnosis, while in other cases, although a specific diagnosis is not achievable, a meaningful limited differential diagnosis can be established. The purpose of this paper is to review the spectrum of malignant fatty tumors, highlighting the current classification system, clinical presentation and behavior, treatment and spectrum of imaging appearances. The imaging review will emphasize CT scanning and MR imaging, and will stress differentiating radiologic features.

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Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224-3899, USA

    Jeffrey J. Peterson, Mark J. Kransdorf & Laura W. Bancroft

  2. Department of Orthopedic Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224-3899, USA

    Mary I. O'Connor

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  1. Jeffrey J. Peterson
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  2. Mark J. Kransdorf
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  3. Laura W. Bancroft
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  4. Mary I. O'Connor
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Correspondence to Mark J. Kransdorf.

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Peterson, J.J., Kransdorf, M.J., Bancroft, L.W. et al. Malignant fatty tumors: classification, clinical course, imaging appearance and treatment. Skeletal Radiol 32, 493–503 (2003). https://doi.org/10.1007/s00256-003-0647-8

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  • DOI: https://doi.org/10.1007/s00256-003-0647-8

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