Abstract
Polyunsaturated fatty acids (PUFAs) play an important role in human diet. Despite the wide-ranging importance and benefits from heart health to brain functions, humans and mammals cannot synthesize PUFAs de novo. The primary sources of PUFA are fish and plants. Due to the increasing concerns associated with food security as well as issues of environmental contaminants in fish oil, there has been considerable interest in the production of polyunsaturated fatty acids from alternative resources which are more sustainable, safer, and economical. For instance, marine bacteria, particularly the genus of Shewanella, Photobacterium, Colwellia, Moritella, Psychromonas, Vibrio, and Alteromonas, are found to be one among the major microbial producers of polyunsaturated fatty acids. Recent developments in the area with a focus on the production of polyunsaturated fatty acids from marine bacteria as well as the metabolic engineering strategies for the improvement of PUFA production are discussed.
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Acknowledgements
We would like to thank Syazwan Ngalimat for his help on the figures.
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This study was funded by research grant number 02-02-14-1500FR under the Fundamental Research Grant Scheme (FRGS) from the Ministry of Higher Education, Government of Malaysia.
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Moi, I.M., Leow, A.T.C., Ali, M.S.M. et al. Polyunsaturated fatty acids in marine bacteria and strategies to enhance their production. Appl Microbiol Biotechnol 102, 5811–5826 (2018). https://doi.org/10.1007/s00253-018-9063-9
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DOI: https://doi.org/10.1007/s00253-018-9063-9