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Functions, applications and production of 2-O-d-glucopyranosyl-l-ascorbic acid

Abstract

Vitamin C (VC) is an essential nutrient that cannot be synthesized by the human body. Due to its extreme instability, various VC derivatives have been developed in an attempt to improve stability while retaining the same biological activity. One of the most important VC derivatives, 2-O-d-glucopyranosyl-l-ascorbic acid (AA-2G), has attracted increasing attention in recent years with a wide range of applications in cosmetics, food, and medicine. In this mini-review, we first introduce the types and properties of different VC glycosyl derivatives. Next, we provide an overview of the functions and applications of AA-2G. Finally, we discuss in-depth the current status and future prospects of AA-2G production by biotransformation.

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Acknowledgments

This project was financially supported by 973 Program (2012CB720802 and 2012CB720806), Key Technologies R & D Program of Jiangsu Province, China (SBE201170459), 111 Project (111-2-06), and the National High Technology Research and Development Program of China (863 Program, 2011AA100905 and SS2012AA022005).

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Correspondence to Long Liu or Jian Chen.

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Han, R., Liu, L., Li, J. et al. Functions, applications and production of 2-O-d-glucopyranosyl-l-ascorbic acid. Appl Microbiol Biotechnol 95, 313–320 (2012). https://doi.org/10.1007/s00253-012-4150-9

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  • DOI: https://doi.org/10.1007/s00253-012-4150-9

Keywords

  • l-ascorbic acid
  • 2-O-d-glucopyranosyl-l-ascorbic acid
  • Applications
  • Biotransformation