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The effect of ozone on the biodegradation of 17α-ethinylestradiol and sulfamethoxazole by mixed bacterial cultures

  • Environmental biotechnology
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Abstract

The potential development of antibacterial resistance and endocrine disruption has led to increased research investigating the removal of contaminants from wastewater (WW) such as sulfamethoxazole (SMX) and 17α-ethinylestradiol (EE2). These compounds react quickly with ozone (O3), thus ozonation during WW treatment may result in their complete removal. Also, O3 has demonstrated the ability to increase the biodegradability of WW and certain pharmaceuticals, suggesting its potential as a pretreatment to activated sludge (AS, biological treatment). The objective of this study was to determine whether ozonation, conducted at doses lower than commonly applied to treated WW, would lead to an increased biodegradability of SMX and EE2. The results show that after ozonation performed at lab-scale the bacterial mixtures removed 5 % to 40 % more SMX; however, 2 % to 23 % less EE2 was removed, which was attributed to the observed preferential degradation of a by-product of EE2 ozonation. These results suggest that although ozonation, used as a pretreatment, was shown in literature to increase the overall biodegradability of AS as well as some specific antibiotic compounds and a blood lipid regulator, the potential for increased removal of pharmaceuticals seems to be compound-dependent and cannot yet be extrapolated to this entire class of compounds.

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Acknowledgments

This work was funded by the McGill Engineering Doctoral Award (MEDA), the J.W. McConnell Foundation, the Natural Sciences and Engineering Research Council of Canada (NSERC), and Health Canada.

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  1. Department of Chemical Engineering, McGill University, 3610 University Street, Montréal, Québec, Canada, H3A 2B2

    Simone Larcher & Viviane Yargeau

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  1. Simone Larcher
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Correspondence to Viviane Yargeau.

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Larcher, S., Yargeau, V. The effect of ozone on the biodegradation of 17α-ethinylestradiol and sulfamethoxazole by mixed bacterial cultures. Appl Microbiol Biotechnol 97, 2201–2210 (2013). https://doi.org/10.1007/s00253-012-4054-8

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