Applied Microbiology and Biotechnology

, Volume 63, Issue 3, pp 282–285 | Cite as

Improved GA1 production by Fusarium fujikuroi

  • J. L. Oller-López
  • J. Avalos
  • A. F. Barrero
  • J. E. OltraEmail author
Short Contribution


Recent studies into gibberellin A1 (GA1) showed it to be physiologically more active than GA3 in plants of great agricultural interest, such as tomatoes, rice, peas, and sweet cherries. We describe here a simple procedure for obtaining large quantities of GA1 (1,500 mg/l) by incubating the FKMC1995 strain of Fusarium fujikuroi in a standard complex medium (SCM). We also compare the GA production of this strain with that of two other wild-type strains of F. fujikuroi (IMI58289, m567) in SCM and low-nitrogen medium and discuss the possible biogenetic mechanisms involved in the over-accumulation of GA1 by FKMC1995.


Sweet Cherry M567 Strain Simple Incubation Mutant SG121 Strain IMI58289 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This research was financed by the European Community (FEDER programme) project 1FD97-1346-C02-01. We thank Prof. E. Cerdá-Olmedo for his collaboration and suggestions, Dr. J. F. Leslie and Dr. B. Tudzynski for strains FKMC1995 and m567 respectively, Dr. M. Muñoz-Dorado for the facilities provided, J. F. Fernández-Sánchez and A. Salinas-Castillo for the spectrofluorimetric analyses, and our English colleague Dr. J. Trout for revising style and grammar. The procedures described here for producing GA1 are covered under Spanish patent P200203050. The experiments here described comply with the current laws of Spain.


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • J. L. Oller-López
    • 1
  • J. Avalos
    • 2
  • A. F. Barrero
    • 1
  • J. E. Oltra
    • 1
    Email author
  1. 1.Departamento de Química Orgánica, Instituto de Biotecnología, Facultad de CienciasUniversidad de GranadaGranadaSpain
  2. 2.Departamento de Genética, Facultad de BiologíaUniversidad de SevillaSevillaSpain

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