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Sequence analysis of pig switch μ, Cμ, and Cμm

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Abstract

 The complete sequence of pig switch μ (Sμ) and the various domains of Cμ, a total of ca 8 kilobases (kb) of sequence, are presented and comparatively analyzed. Sμ starts about 2.5 kb downstream of the single pig J H gene and ends 0.4 kb upstream of Cμ; the length of Sμ is 3.2 kb. Three major pentameric repeats, gagct, gggct, and gggtt, comprise more than half of the entire Sμ sequence. The two most frequent decamers are gagctgagct and gagctgggct. The longest single repeated sequence is 93 base pairs. The frequency of the various pentamers indicates that pig Sμ is more similar to human Sμ than to mouse Sμ.

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Authors and Affiliations

  1. Department of Microbiology, The University of Iowa, Iowa City, IA 52242-1109, USA, , , , , , US

    Jishan Sun & J. E. Butler

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  1. Jishan Sun
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  2. J. E. Butler
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Received: 23 November 1996 / Revised: 21 April 1997

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Sun, J., Butler, J. Sequence analysis of pig switch μ, Cμ, and Cμm . Immunogenetics 46, 452–460 (1997). https://doi.org/10.1007/s002510050305

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  • DOI: https://doi.org/10.1007/s002510050305

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