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MR1 discovery

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Abstract

The moment of MR1 discovery is described. The MR1 gene is the first and the last reported human MHC-related gene intentionally isolated from the human genome composed of three billion base pairs. Evolutionary considerations formed the basis of its isolation. Some details surrounding the moment and some retrospective descriptions with various kinds of encounters are also included.

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Authors and Affiliations

  1. Department of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan

    Keiichiro Hashimoto

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  1. Keiichiro Hashimoto
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Correspondence to Keiichiro Hashimoto.

Additional information

This article is published in the Special Issue CD1, MR1, NKT, and MAIT: Evolution and Origins of Non-peptidic Antigen Recognition by T lymphocytes with Guest Editor Dr. Dirk Zajonc.

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Hashimoto, K. MR1 discovery. Immunogenetics 68, 491–498 (2016). https://doi.org/10.1007/s00251-016-0943-9

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  • DOI: https://doi.org/10.1007/s00251-016-0943-9

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