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Immunogenetics

, Volume 68, Issue 10, pp 749–753 | Cite as

Significance of positive selection and gene duplication in adaptive evolution: in memory of Austin L. Hughes

  • Ken WolfeEmail author
  • Colm Ó’hUigín
Mini Review

Abstract

In this minireview, we highlight the contributions of the late Austin L. Hughes to two areas of molecular evolution: the role of positive (Darwinian) selection, and the impact of gene duplications during genome evolution.

Keywords

Selection Duplication Evolution 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.UCD Conway Institute and School of MedicineUniversity College DublinDublin 4Ireland
  2. 2.Cancer Inflammation Program, Laboratory of Experimental Immunology, Leidos-Frederick, IncorporatedFrederick National Laboratory for Cancer ResearchFrederickUSA

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