Abstract
Magnetic resonance elastography is a relatively new, rapidly evolving quantitative magnetic resonance imaging technique which can be used for mapping the viscoelastic mechanical properties of soft tissues. MR elastography measurements are akin to manual palpation but with the advantages of both being quantitative and being useful for regions which are not available for palpation, such as the human brain. MR elastography is noninvasive, well tolerated, and complements standard radiological and histopathological studies by providing in vivo measurements that reflect tissue microstructural integrity. While brain MR elastography studies in adults are becoming frequent, published studies on the utility of MR elastography in children are sparse. In this review, we have summarized the major scientific principles and recent clinical applications of brain MR elastography in diagnostic neuroscience and discuss avenues for impact in assessing the pediatric brain.
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This work was supported in part by the Delaware INBRE program (P20-GM103446) and the Delaware CTR program (U54-GM104941).
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AMK wrote the manuscript; GM, CLJ, and RMN edited the manuscript; all authors reviewed and approved the manuscript.
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Abdulhafeez M Khair: Nothing to disclose.
Grace McIlvain: Nothing to disclose.
Matthew DJ McGarry: Nothing to disclose.
Vinay Kandula: Nothing to disclose.
Xuyi Yue: Nothing to disclose.
Gurcharanjeet Kaur: Nothing to disclose.
Lauren W Averill: Nothing to disclose.
Arabinda K Choudhary: Nothing to disclose.
Curtis L Johnson: Nothing to disclose.
Rahul M Nikam: Nothing to disclose.
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Khair, A.M., McIlvain, G., McGarry, M.D.J. et al. Clinical application of magnetic resonance elastography in pediatric neurological disorders. Pediatr Radiol 53, 2712–2722 (2023). https://doi.org/10.1007/s00247-023-05779-3
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DOI: https://doi.org/10.1007/s00247-023-05779-3