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Lung infections in immunocompromised children

  • ESPR Belgrade 2023 - Postgraduate Course and Taskforce Lectures
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Abstract

Pulmonary infection is the leading cause of infectious morbidity and mortality in children with immune defects. We provide a comprehensive review of lung infections in immunocompromised children, with a focus on imaging findings and imaging-based management. We include an overview of the immune defences of the respiratory tract, the aetiologies of immune defects in children, the features of specific infections and important differential diagnoses and describe diagnostic strategies using imaging and non-imaging-based techniques.

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Authors and Affiliations

  1. Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK

    Alistair D. Calder & Giulia Perucca

  2. Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

    Sarah May Johnson & Karyn Moshal

  3. Immunology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

    Ashwin R. Pandey & Maaike A. Kusters

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  1. Alistair D. Calder
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  2. Giulia Perucca
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  3. Sarah May Johnson
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  4. Ashwin R. Pandey
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  5. Karyn Moshal
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  6. Maaike A. Kusters
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Contributions

A.D.C. conceived and supervised the paper, reviewed the literature, collected cases, prepared the initial draft of the manuscript and collated other authors’ contributions. G.P., S.M.J. and A.R.P. reviewed the literature, revised the manuscript and provided cases. K.M. and M.A.K. conceived the paper, provided cases and revised the manuscript. All authors reviewed and approved the final manuscript.

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Correspondence to Alistair D. Calder.

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Calder, A.D., Perucca, G., Johnson, S.M. et al. Lung infections in immunocompromised children. Pediatr Radiol 54, 530–547 (2024). https://doi.org/10.1007/s00247-023-05735-1

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