Abstract
Blastomycosis is caused by Blastomyces dermatitidis, a thermally dimorphic fungus that lives in the form of spores in the soil in North America. The main mode of transmission is through the inhalation of these spores. Despite the importance of knowing the imaging characteristics of blastomycosis given the suggested high rates of dissemination in symptomatic children, a paucity of literature focuses on the imaging patterns of blastomycosis in the pediatric population. In this review, we describe the main imaging findings of pediatric pulmonary blastomycosis and briefly review extrapulmonary manifestations of the disease. Familiarity with these imaging manifestations is important to aid in rapid diagnosis.
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References
Fanella S, Skinner S, Trepman E, Embil JM (2011) Blastomycosis in children and adolescents: a 30-year experience from Manitoba. Med Mycol 49:627–632
Anderson EJ, Ahn PB, Yogev R et al (2013) Blastomycosis in children: a study of 14 cases. J Pediatr Infect Dis Soc 2:386–390
Rozovsky K, Bunge M, Higgins R et al (2019) Imaging patterns of pediatric pulmonary blastomycosis. AJR Am J Roentgenol 212:905–913
Frost HM, Anderson J, Ivacic L, Meece J (2017) Blastomycosis in children: an analysis of clinical, epidemiologic, and genetic features. J Pediatr Infect Dis Soc 6:49–56
Saccente M, Woods GL (2010) Clinical and laboratory update on blastomycosis. Clin Microbiol Rev 23:367–368
Alkrinawi S, Reed MH, Pasterkamp H (1995) Pulmonary blastomycosis in children: findings on chest radiographs. AJR Am J Roentgenol 165:651–654
Sheflin JR, Campbell JA, Thompson GP (1990) Pulmonary blastomycosis: findings on chest radiographs in 63 patients. AJR Am J Roentgenol 154:1177–1180
Ronald S, Strzelczyk J, Moore S et al (2009) Computed tomographic scan evaluation of pulmonary blastomycosis. Can J Infect Dis Med Microbiol 20:112–116
Fang W, Washington L, Kumar N (2007) Imaging manifestations of blastomycosis: a pulmonary infection with potential dissemination. Radiographics 27:641–655
Pelly L, Al Juaid A, Fanella S (2014) Severe blastomycosis in infants. Pediatr Infect Dis J 33:1189–1191
Chapman SW (2005) Blastomyces dermatitidis. In: Mandell JN, Bennett JE, Dolin R (eds) Mandell, Douglas, and Bennett’s principles and practice of infectious diseases, 6th edn. Elsevier, Philadelphia, pp 3026–3040
Gauthier G, Klein BS (2014) Chapter 198 — blastomycosis. In: Cherry JD, Harrison GJ (eds) Feigin and Cherry’s textbook of pediatric infectious disease, 7th edn. Elsevier Saunders, Philadelphia, pp 2723–2743
Brick KE, Drolet BA, Lyon VB, Galbraith SS (2013) Cutaneous and disseminated blastomycosis: a pediatric case series. Pediatr Dermatol 30:23–28
Oppenheimer M, Embil JM, Black B et al (2007) Blastomycosis of bones and joints. South Med J 100:570–578
Guler N, Palanduz A, Ones U et al (1995) Progressive vertebral blastomycosis mimicking tuberculosis. Pediatr Infect Dis J 14:816–818
Saccente M, Abernathy RS, Pappas PG et al (1998) Vertebral blastomycosis with paravertebral abscess: report of eight cases and review of the literature. Clin Infect Dis 26:413–418
Teijido J, Drendel AL (2019) Disseminated blastomycosis in a teenager presenting with pleural effusion and splenomegaly. J Emerg Med 56:e23–e26
Hamann JC, Marberry K (2010) Sentinel presentation of disseminated Blastomyces dermatitidis infection as hip pain in a young adult: a case report. J Bone Joint Surg Am 92:469–472
Rucci J, Eisinger G, Miranda-Gomez G, Nguyen J (2014) Blastomycosis of the head and neck. Am J Otolaryngol 35:390–395
Farr RC, Gardner G, Acker JD et al (1992) Blastomycotic cranial osteomyelitis. Am J Otol 13:582–586
Bariola JR, Perry P, Pappas PG et al (2010) Blastomycosis of the central nervous system: a multicenter review of diagnosis and treatment in the modern era. Clin Infect Dis 50:797–804
Abrams E, Dean HJ, Bunge MK et al (2011) Blastomycosis of the central nervous system in a child: a rare cause of hypopituitarism. J Pediatr Endocrinol Metab 24:775–777
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Rozovsky, K., Moffatt, H. Imaging findings of pulmonary blastomycosis in pediatric patients. Pediatr Radiol 52, 1974–1984 (2022). https://doi.org/10.1007/s00247-022-05402-x
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DOI: https://doi.org/10.1007/s00247-022-05402-x