Abstract
Fetal MRI allows for earlier and better detection of complex congenital anomalies. However, its diagnostic utility is often limited by technical barriers that introduce artifacts and reduce image quality. The main determinants of fetal MR image quality are speed of acquisition, spatial resolution and signal-to-noise ratio (SNR). Imaging optimization is a challenge because a change to improve one scan parameter often leads to worsening of another. Moreover, the recent introduction of fetal MRI on 3-tesla (T) scanners to achieve better SNR can amplify some technical issues. Motion, banding artifacts and aliasing artifacts impact the quality of fetal acquisitions at any field strength. High specific absorption rate (SAR) and artifacts from inhomogeneities in the radiofrequency field are important limitations of high-field-strength imaging. We discuss technical barriers that impact image quality and are important limitations to prenatal MRI diagnosis, and propose solutions to improve image quality and reduce artifacts.
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Prayer D, Malinger G, Brugger PC et al (2017) ISUOG practice guidelines: performance of fetal magnetic resonance imaging. Ultrasound Obstet Gynecol 49:671–680
Platt LD, Barth RA, Pugash D (2018) Current controversies in prenatal diagnosis 3: fetal MRI should be performed in all prenatally detected fetuses with a major structural abnormality. Prenat Diagn 38:166–172
Weisstanner C, Gruber GM, Brugger PC et al (2017) Fetal MRI at 3T — ready for routine use? Br J Radiol 90:20160362
Malamateniou C, Malik SJ, Counsell SJ et al (2013) Motion-compensation techniques in neonatal and fetal MR imaging. AJNR Am J Neuroradiol 34:1124–1136
Gholipour A, Estroff JA, Barnewolt CE et al (2014) Fetal MRI: a technical update with educational aspirations. Concepts Magn Reson Part A Bridge Educ Res 43:237–266
Barth MM, Smith MP, Pedrosa I et al (2007) Body MR imaging at 3.0 T: understanding the opportunities and challenges. Radiographics 27:1445–1462
Merkle EM, Dale BM (2006) Abdominal MRI at 3.0 T: the basics revisited. AJR Am J Roentgenol 186:1524–1532
Gruber B, Froeling M, Leiner T, Klomp DWJ (2018) RF coils: a practical guide for nonphysicists. J Magn Reson Imaging 48:590–604
Huang SY, Seethamraju RT, Patel P et al (2015) Body MR imaging: artifacts, k-space, and solutions. Radiographics 35:1439–1460
Chang KJ, Kamel IR, Macura KJ, Bluemke DA (2008) 3.0-T MR imaging of the abdomen: comparison with 1.5 T. Radiographics 28:1983–1998
Victoria T, Johnson AM, Edgar JC et al (2016) Comparison between 1.5-T and 3-T MRI for fetal imaging: is there an advantage to imaging with a higher field strength? AJR Am J Roentgenol 206:195–201
Victoria T, Jaramillo D, Roberts TPL et al (2014) Fetal magnetic resonance imaging: jumping from 1.5 to 3 tesla (preliminary experience). Pediatr Radiol 44:376–386
Dagia C, Ditchfield M (2008) 3T MRI in paediatrics: challenges and clinical applications. Eur J Radiol 68:309–319
Priego G, Barrowman NJ, Hurteau-Miller J, Miller E (2017) Does 3T fetal MRI improve image resolution of normal brain structures between 20 and 24 weeks’ gestational age? AJNR Am J Neuroradiol 38:1636–1642
Jaimes C, Delgado J, Cunnane MB et al (2019) Does 3-T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3 T. Pediatr Radiol 49:37–45
Chartier AL, Bouvier MJ, McPherson DR et al (2019) The safety of maternal and fetal MRI at 3T. AJR Am J Roentgenol 213:1170–1173
Welsh RC, Nemec U, Thomason ME (2011) Fetal magnetic resonance imaging at 3.0 T. Top Magn Reson Imaging 22:119–131
Hand JW, Li Y, Thomas EL et al (2006) Prediction of specific absorption rate in mother and fetus associated with MRI examinations during pregnancy. Magn Reson Med 55:883–893
Tsai LL, Grant AK, Mortele KJ et al (2015) A practical guide to MR imaging safety: what radiologists need to know. Radiographics 35:1722–1737
Alsop DC (1997) The sensitivity of low flip angle RARE imaging. Magn Reson Med 37:176–184
Hennig J, Scheffler K (2000) Easy improvement of signal-to-noise in RARE-sequences with low refocusing flip angles. Magn Reson Med 44:983–985
Guo W-Y, Ono S, Oi S et al (2006) Dynamic motion analysis of fetuses with central nervous system disorders by cine magnetic resonance imaging using fast imaging employing steady-state acquisition and parallel imaging: a preliminary result. J Neurosurg 105:94–100
Ohliger MA, Sodickson DK (2006) An introduction to coil array design for parallel MRI. NMR Biomed 19:300–315
Parikh PT, Sandhu GS, Blackham KA et al (2011) Evaluation of image quality of a 32-channel versus a 12-channel head coil at 1.5 T for MR imaging of the brain. AJNR Am J Neuroradiol 32:365–373
Keil B, Wald LL (2013) Massively parallel MRI detector arrays. J Magn Reson 229:75–89
Arena L, Morehouse HT, Safir J (1995) MR imaging artifacts that simulate disease: how to recognize and eliminate them. Radiographics 15:1373–1394
da Silva NA, Vassallo J, Sarian LO et al (2018) Magnetic resonance imaging of the fetal brain at 3 tesla: preliminary experience from a single series. Medicine 97:e12602
Gholipour A, Estroff JA, Warfield SK (2010) Robust super-resolution volume reconstruction from slice acquisitions: application to fetal brain MRI. IEEE Trans Med Imaging 29:1739–1758
Pier DB, Gholipour A, Afacan O et al (2016) 3D super-resolution motion-corrected MRI: validation of fetal posterior fossa measurements. J Neuroimaging 26:539–544
Velasco-Annis C, Gholipour A, Afacan O et al (2015) Normative biometrics for fetal ocular growth using volumetric MRI reconstruction. Prenat Diagn 35:400–408
Gholipour A, Rollins CK, Velasco-Annis C et al (2017) A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. Sci Rep 7:476
Marami B, Mohseni Salehi SS, Afacan O et al (2017) Temporal slice registration and robust diffusion-tensor reconstruction for improved fetal brain structural connectivity analysis. Neuroimage 156:475–488
Khan S, Vasung L, Marami B et al (2019) Fetal brain growth portrayed by a spatiotemporal diffusion tensor MRI atlas computed from in utero images. Neuroimage 185:593–608
Heiland S (2008) From a as in aliasing to Z as in zipper: artifacts in MRI. Clin Neuroradiol 18:25–36
Glenn OA, Barkovich AJ (2006) Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1. AJNR Am J Neuroradiol 27:1604–1611
Scheffler K, Lehnhardt S (2003) Principles and applications of balanced SSFP techniques. Eur Radiol 13:2409–2418
Hargreaves B (2012) Rapid gradient-echo imaging. J Magn Reson Imaging 36:1300–1313
Graves MJ, Mitchell DG (2013) Body MRI artifacts in clinical practice: a physicist’s and radiologist’s perspective. J Magn Reson Imaging 38:269–287
Homann H, Graesslin I, Eggers H et al (2012) Local SAR management by RF shimming: a simulation study with multiple human body models. MAGMA 25:193–204
Webb AG (2011) Dielectric materials in magnetic resonance. Concepts Magn Reson 38A:148–184
Childs AS, Malik SJ, O’Regan DP, Hajnal JV (2013) Impact of number of channels on RF shimming at 3T. MAGMA 26:401–410
Abaci Turk E, Yetisir F, Adalsteinsson E et al (2020) Individual variation in simulated fetal SAR assessed in multiple body models. Magn Reson Med 83:1418–1428
Brink WM, Gulani V, Webb AG (2015) Clinical applications of dual-channel transmit MRI: a review. J Magn Reson Imaging 42:855–869
Vernickel P, Röschmann P, Findeklee C et al (2007) Eight-channel transmit/receive body MRI coil at 3T. Magn Reson Med 58:381–389
Garcia-Polo P, Gagoski B, Guerin B et al (2015) An anthropomorphic MR phantom of the gravid abdomen including the uterus, placenta, fetus and fetal brain. ISMRM Annual Meeting, Toronto
Murbach M, Cabot E, Neufeld E et al (2011) Local SAR enhancements in anatomically correct children and adult models as a function of position within 1.5 T MR body coil. Prog Biophys Mol Biol 107:428–433
Murbach M, Neufeld E, Samaras T et al (2017) Pregnant women models analyzed for RF exposure and temperature increase in 3TRF shimmed birdcages: impact of RF shimming on MRI exposure of pregnant women. Magn Reson Med 77:2048–2056
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Machado-Rivas, F., Jaimes, C., Kirsch, J.E. et al. Image-quality optimization and artifact reduction in fetal magnetic resonance imaging. Pediatr Radiol 50, 1830–1838 (2020). https://doi.org/10.1007/s00247-020-04672-7
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DOI: https://doi.org/10.1007/s00247-020-04672-7