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Allergic-like contrast media reaction management in children


The use of contrast materials as part of imaging examinations is common in children of all ages, as these compounds increase image contrast, lesion detection and lesion characterization. Though modern iodinated, gadolinium-based and ultrasound microbubble contrast materials generally are quite safe, acute physiological and allergic-like reactions are possible. The majority of acute contrast reactions in children are mild and self-limited; however, life-threatening reactions can occur. It is our obligation as radiologists to recognize and manage these adverse reactions. The objective of this article is to review the frequency, manifestations and appropriate treatment of acute contrast reactions in the pediatric population.

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Correspondence to Jonathan R. Dillman.

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Conflicts of interest

Drs. Dillman and Trout receive funding from Guerbet regarding clinical trial design. Dr. Dillman also receives funding from Bracco Diagnostics related to contrast-enhanced ultrasound. Dr. Davenport has no disclosures.

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Dillman, J.R., Trout, A.T. & Davenport, M.S. Allergic-like contrast media reaction management in children. Pediatr Radiol 48, 1688–1694 (2018).

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  • Allergic-like reaction
  • Anaphylactoid reaction
  • Children
  • Contrast material
  • Contrast reaction
  • Treatment