Pediatric Radiology

, Volume 48, Issue 12, pp 1688–1694 | Cite as

Allergic-like contrast media reaction management in children

  • Jonathan R. DillmanEmail author
  • Andrew T. Trout
  • Matthew S. Davenport


The use of contrast materials as part of imaging examinations is common in children of all ages, as these compounds increase image contrast, lesion detection and lesion characterization. Though modern iodinated, gadolinium-based and ultrasound microbubble contrast materials generally are quite safe, acute physiological and allergic-like reactions are possible. The majority of acute contrast reactions in children are mild and self-limited; however, life-threatening reactions can occur. It is our obligation as radiologists to recognize and manage these adverse reactions. The objective of this article is to review the frequency, manifestations and appropriate treatment of acute contrast reactions in the pediatric population.


Allergic-like reaction Anaphylactoid reaction Children Contrast material Contrast reaction Treatment 


Compliance with ethical standards

Conflicts of interest

Drs. Dillman and Trout receive funding from Guerbet regarding clinical trial design. Dr. Dillman also receives funding from Bracco Diagnostics related to contrast-enhanced ultrasound. Dr. Davenport has no disclosures.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Radiology, ML 5031Cincinnati Children’s Hospital Medical CenterCincinnatiUSA
  2. 2.Department of RadiologyUniversity of Cincinnati College of MedicineCincinnatiUSA
  3. 3.Department of RadiologyUniversity of Michigan Health SystemAnn ArborUSA

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