Pediatric Radiology

, Volume 47, Issue 13, pp 1828–1838 | Cite as

Imaging patterns of venous-related brain injury in children

  • Luke L. Linscott
  • James L. Leach
  • Blaise V. Jones
  • Todd A. Abruzzo
Pictorial Essay
  • 70 Downloads

Abstract

Venous-related brain injury is a common form of cerebrovascular injury in children and encompasses a diverse group of cerebrovascular diagnoses. The purpose of this pictorial essay is to introduce the relevant anatomy, pathophysiology and various imaging patterns of venous-related cerebral injury in children. Unifying concepts to better understand the effects of venous hypertension in the developing brain will be emphasized. These unifying concepts will provide the imaging professional with a conceptual framework to better understand and confidently identify imaging patterns of venous-related cerebral injury.

Keywords

Brain injury Children Vascular malformation Venous thrombosis Venous 

Notes

Compliance with ethical standards

Conflicts of interest

None.

References

  1. 1.
    Meder JF, Chiras J, Roland J et al (1994) Venous territories of the brain. J Neuroradiol 21:118–133PubMedGoogle Scholar
  2. 2.
    Fries G, Wallenfang T, Hennen J et al (1992) Occlusion of the pig superior sagittal sinus, bridging and cortical veins: multistep evolution of sinus-vein thrombosis. J Neurosurg 77:127–133CrossRefPubMedGoogle Scholar
  3. 3.
    Leach JL, Fortuna RB, Jones BV, Gaskill-Shipley MF (2006) Imaging of cerebral venous thrombosis: current techniques, spectrum of findings, and diagnostic pitfalls. Radiographics 26(Suppl 1):S19–S41 discussion S42–43CrossRefPubMedGoogle Scholar
  4. 4.
    Tsai FY, Wang AM, Matovich VB et al (1995) The staging of acute dural sinus thrombosis - correlation with venous-pressure measurements and implications for treatment and prognosis. AJNR Am J Neuroradiol 16:1021–1029PubMedGoogle Scholar
  5. 5.
    Gotoh M, Ohmoto T, Kuyama H (1993) Experimental study of venous circulatory disturbance by dural sinus occlusion. Acta Neurochir 124:120–126CrossRefPubMedGoogle Scholar
  6. 6.
    Yoshikawa T, Abe O, Tsuchiya K et al (2002) Diffusion-weighted magnetic resonance imaging of dural sinus thrombosis. Neuroradiology 44:481–488CrossRefPubMedGoogle Scholar
  7. 7.
    Lovblad KO, Bassetti C, Schneider J et al (2000) Diffusion-weighted MRI suggests the coexistence of cytotoxic and vasogenic oedema in a case of deep cerebral venous thrombosis. Neuroradiology 42:728–731CrossRefPubMedGoogle Scholar
  8. 8.
    Forbes KP, Pipe JG, Heiserman JE (2001) Evidence for cytotoxic edema in the pathogenesis of cerebral venous infarction. AJNR Am J Neuroradiol 22:450–455PubMedGoogle Scholar
  9. 9.
    Ducreux D, Oppenheim C, Vandamme X et al (2001) Diffusion-weighted imaging patterns of brain damage associated with cerebral venous thrombosis. AJNR Am J Neuroradiol 22:261–268PubMedGoogle Scholar
  10. 10.
    Thomalla G, Schwark C, Sobesky J et al (2006) Outcome and symptomatic bleeding complications of intravenous thrombolysis within 6 hours in MRI-selected stroke patients: comparison of a German multicenter study with the pooled data of ATLANTIS, ECASS, and NINDS tPA trials. Stroke 37:852–858CrossRefPubMedGoogle Scholar
  11. 11.
    Kumral E, Polat F, Uzunkopru C et al (2012) The clinical spectrum of intracerebral hematoma, hemorrhagic infarct, non-hemorrhagic infarct, and non-lesional venous stroke in patients with cerebral sinus-venous thrombosis. Eur J Neurol 19:537–543CrossRefPubMedGoogle Scholar
  12. 12.
    Volpe JJ (2009) Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol 8:110–124CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Raybaud C, Ahmad T, Rastegar N et al (2013) The premature brain: developmental and lesional anatomy. Neuroradiology 55(Suppl 2):23–40CrossRefPubMedGoogle Scholar
  14. 14.
    Arrigoni F, Parazzini C, Righini A et al (2011) Deep medullary vein involvement in neonates with brain damage: an MR imaging study. AJNR Am J Neuroradiol 32:2030–2036CrossRefPubMedGoogle Scholar
  15. 15.
    Marti-Bonmati L, Menor F, Mulas F (1993) The Sturge-Weber syndrome - correlation between the clinical status and radiological CT and MRI findings. Childs Nerv Syst 9:107–109CrossRefPubMedGoogle Scholar
  16. 16.
    Tournut P, Turjman F, Guibal AL et al (1992) MRI in Sturge-Weber syndrome. J Neuroradiol 19:285–292PubMedGoogle Scholar
  17. 17.
    Recinos PF, Rahmathulla G, Pearl M et al (2012) Vein of Galen malformations: epidemiology, clinical presentations, management. Neurosurg Clin N Am 23:165–177CrossRefPubMedGoogle Scholar
  18. 18.
    Parsa CF (2013) Focal venous hypertension as a pathophysiologic mechanism for tissue hypertrophy, port-wine stains, the Sturge-Weber syndrome, and related disorders: proof of concept with novel hypothesis for underlying etiological cause (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 111:180–215PubMedPubMedCentralGoogle Scholar
  19. 19.
    Meila D, Grieb D, Melber K et al (2016) Hydrocephalus in vein of Galen malformation: etiologies and therapeutic management implications. Acta Neurochir 7:1279–1284CrossRefGoogle Scholar
  20. 20.
    Ramonet D, Pugliese M, Rodriguez MJ et al (2002) Calcium precipitation in acute and chronic brain diseases. J Physiol Paris 96:307–312CrossRefPubMedGoogle Scholar
  21. 21.
    Rodriguez MJ, Ursu G, Bernal F et al (2001) Perinatal human hypoxia-ischemia vulnerability correlates with brain calcification. Neurobiol Dis 8:59–68CrossRefPubMedGoogle Scholar
  22. 22.
    Wu J, Tarabishy B, Hu JN et al (2011) Cortical calcification in Sturge-weber syndrome on MRI-SWI: relation to brain perfusion status and seizure severity. J Magn Reson Imaging 34:791–798CrossRefPubMedPubMedCentralGoogle Scholar
  23. 23.
    Bansal A, Gailloud P, Jordan L, Ruiz DS (2009) Regression of cerebral calcifications after endovascular treatment in a case of vein of Galen arteriovenous malformation. Case Report J Neurosurg Pediatr 4:17–20CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Department of Radiology, Primary Children’s HospitalUniversity of Utah School of MedicineSalt Lake CityUSA
  2. 2.Department of Radiology, Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiUSA

Personalised recommendations