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Epithelioid hemangioma of bone: radiologic and magnetic resonance imaging characteristics with histopathological correlation

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Abstract

Background

Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis.

Objective

To review three cases of epithelioid hemangioma of bone occurring in pediatric patients involving the epiphysis and to explore the imaging features of this tumor.

Materials and methods

Retrospectively review three cases of epithelioid hemangioma occurring in skeletally immature patients.

Results

These tumors primarily involved the epiphyses or epiphyseal equivalent bones. One lesion was centered in the metaphysis but extended to the epiphysis. These are three cases presenting in an unusual location and at an unusual age.

Conclusion

Epithelioid hemangioma, though rare, can occur in pediatric patients and appears to involve the epiphyses in these patients. This is in contrast to the usual age and location reported. Epithelioid hemangioma may be considered for an epiphyseal lesion in a skeletally immature patient.

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Authors and Affiliations

  1. Department of Radiology, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA

    Kathleen Schenker & Steven Blumer

  2. Department of Radiology, Nicklaus Children’s Hospital, Miami, FL, USA

    Diego Jaramillo

  3. Departments of Pathology and Laboratory Medicine, Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA

    Amanda L. Treece

  4. Department of Radiology, Monroe Carell Jr. Children’s Hospital at Vanderbilt, 2200 Children’s Way, Suite 1422, Nashville, TN, 37232, USA

    Aashim Bhatia

Authors
  1. Kathleen Schenker
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  2. Steven Blumer
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  3. Diego Jaramillo
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  4. Amanda L. Treece
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  5. Aashim Bhatia
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Corresponding author

Correspondence to Aashim Bhatia.

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Schenker, K., Blumer, S., Jaramillo, D. et al. Epithelioid hemangioma of bone: radiologic and magnetic resonance imaging characteristics with histopathological correlation. Pediatr Radiol 47, 1631–1637 (2017). https://doi.org/10.1007/s00247-017-3922-x

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  • DOI: https://doi.org/10.1007/s00247-017-3922-x

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