Pediatric Radiology

, Volume 40, Issue 6, pp 850–858 | Cite as

Chronic diseases of lung parenchyma in children: the role of imaging

  • K. Haran JogeesvaranEmail author
  • Catherine M. Owens


Chronic diseases of the lung parenchyma (CDoLP) in children encompass a vast number of distinct clinico-pathological conditions. The prevalence of CDoLP has continued to increase in the last 10–15 years and the paediatric radiologist will therefore have to become more familiar with the imaging appearances of CDoLP. This review highlights some of the key imaging appearances of CDoLP, focussing mainly on airways disease. We also explore issues around technique optimisation and dose minimisation that remain of paramount importance in children.


Lung Chest US CT MRI Child 


  1. 1.
    Baraldi E, Filippone M (2007) Chronic Lung Disease after Premature Birth. N Engl J Med 357:1946–1955CrossRefPubMedGoogle Scholar
  2. 2.
    Hack M, Fanaroff AA (2000) Outcomes of children of extremely low birthweight and gestational age in the 1990s. Semin Neonatol 5:89–106CrossRefPubMedGoogle Scholar
  3. 3.
    Klusmann M, Owens C (2009) HRCT in paediatric diffuse interstitial lung disease—a review for 2009. Pediatr Radiol 39:471–481CrossRefPubMedGoogle Scholar
  4. 4.
    Copley SJ, Coren M, Nicholson AJ et al (2000) Diagnostic accuracy of thin-section computed tomography and chest radiography in paediatric interstitial lung disease. AJR 174:549–554PubMedGoogle Scholar
  5. 5.
    Owens C (2004) Radiology of diffuse interstitial pulmonary disease in children. Eur Radiol 14:L2–12CrossRefPubMedGoogle Scholar
  6. 6.
    Bastos M, Lee EY, Strauss KJ et al (2009) Motion artifact on high-resolution CT images of pediatric patients: comparison of volumetric and axial CT methods. AJR 193:1414–1418CrossRefPubMedGoogle Scholar
  7. 7.
    Puderbach M, Kauczor HU (2008) Can lung MR replace lung CT? Pediatr Radiol 38:S439–451CrossRefPubMedGoogle Scholar
  8. 8.
    Lee EY (2008) Advancing CT and MR imaging of the lungs and airways in children: imaging into practice. Pediatr Radiol 38:S208–212CrossRefPubMedGoogle Scholar
  9. 9.
    Hirsch W, Sorge I, Krohmer S et al (2008) MRI of the lungs in children. Eur J Radiol 68:278–288CrossRefPubMedGoogle Scholar
  10. 10.
    Bhandari A, Bhandari V (2009) Pitfalls, problems, and progress in bronchopulmonary dysplasia. Pediatrics 123:1562–1573CrossRefPubMedGoogle Scholar
  11. 11.
    Howling SJ, Northway WH Jr, Hansell DM et al (2000) Pulmonary sequelae of bronchopulmonary dysplasia survivors: high-resolution CT findings. AJR 174:1323–1326PubMedGoogle Scholar
  12. 12.
    Rossi UG, Owens CM (2005) The radiology of chronic lung disease in children. Arch Dis Child 90:601–607CrossRefPubMedGoogle Scholar
  13. 13.
    Aukland SM, Halvorsen T, Fosse KR et al (2006) High-resolution CT of the chest in children and young adults who were born prematurely: findings in a population-based Study. AJR 187:1012–1018CrossRefPubMedGoogle Scholar
  14. 14.
    Mahut B, De Blic J, Emond S et al (2007) Chest computed tomography findings in bronchopulmonary dysplasia and correlation with lung function. Arch Dis Child Fetal Neonatal Ed 92:F459–F464CrossRefPubMedGoogle Scholar
  15. 15.
    Aukland SM, Rosendahl K, Owens CM et al (2009) Neonatal bronchopulmonary dysplasia predicts abnormal pulmonary HRCT scans in long-term survivors of extreme preterm birth. Thorax 64:405–410CrossRefPubMedGoogle Scholar
  16. 16.
    Stocks J (2008) Late lung disease in bronchopulmonary dysplasia—lessons learned from lung function testing. European Paediatrics 2:31–34Google Scholar
  17. 17.
    Santamaria F, Montella S, Camera L et al (2006) Lung structure abnormalities but normal lung function in pediatric bronchiectasis. Chest 130:480–486CrossRefPubMedGoogle Scholar
  18. 18.
    Li AM, Sonnappa S, Lex C et al (2005) Non-CF bronchiectasis: does knowing the aetiology lead to changes in management? Eur Respir J 26:8–14CrossRefPubMedGoogle Scholar
  19. 19.
    Mason AC, Nakielna BE (1999) Newly diagnosed cystic fibrosis in adults: pattern and distribution of bronchiectasis in 12 Cases. Clin Radiol 54:507–512CrossRefPubMedGoogle Scholar
  20. 20.
    Aziz ZA, Davies JC, Alton EW et al (2007) Computed tomography and cystic fibrosis: promises and problems. Thorax 62:181–186CrossRefPubMedGoogle Scholar
  21. 21.
    Ellis SM, Hansell DM (2002) Imaging of non-tuberculous (atypical) mycobacterial pulmonary infection. Clin Radiol 57:661–669CrossRefPubMedGoogle Scholar
  22. 22.
    Boesch RP, Daines C, Willging JP et al (2006) Advances in the diagnosis and management of chronic pulmonary aspiration in children. Eur Respir J 28:847–861CrossRefPubMedGoogle Scholar
  23. 23.
    Lynch DA, Hay T, Newell JD et al (1999) Pediatric diffuse lung disease: diagnosis and classification using high-resolution CT. AJR 173:713–718PubMedGoogle Scholar
  24. 24.
    Clement A, Task Force ERS (2004) Task force on chronic interstitial lung disease in immunocompetent children. Eur Respir J 24:686–697CrossRefPubMedGoogle Scholar
  25. 25.
    Deutsch GH, Young LR, Deterding RR et al (2007) Diffuse lung disease in young children: application of a novel classification scheme. Am J Respir Crit Care Med 176:1120–1128CrossRefPubMedGoogle Scholar
  26. 26.
    Koh DM, Hansell DM (2000) Computed Tomography of Diffuse Interstitial Lung Disease in Children. Clin Radiol 55:659–667CrossRefPubMedGoogle Scholar
  27. 27.
    Vrielynck S, Mamou-Mani T, Emond S et al (2008) Diagnostic value of high-resolution CT in the evaluation of chronic infiltrative lung disease in children. AJR 191:914–920CrossRefPubMedGoogle Scholar
  28. 28.
    Brody AS (2008) New perspectives in imaging interstitial lung disease in children. Pediatr Radiol 38:S205–207CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  1. 1.Radiology DepartmentGreat Ormond Street HospitalLondonUK

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