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Xanthogranulomatous pyelonephritis: an uncommon pediatric renal mass

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Abstract

Xanthogranulomatous pyelonephritis (XGP) is a chronic suppurative infectious process that only rarely affects pediatric patients, and most commonly occurs in the setting of a large obstructing calculus. Histologically, XGP is characterized by the presence of chronic inflammation and lipid-laden macrophages. This case report illustrates the radiological, surgical, and pathologic findings in a young patient who presented to our institution for treatment of this uncommon condition. Although rare, xanthogranulomatous pyelonephritis is a clinically important entity that can affect pediatric patients. This condition should be considered in the differential diagnosis for an atypical-appearing renal mass.

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Acknowledgement

The authors would like to acknowledge Peter J. Strouse, M.D., for his support.

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Authors and Affiliations

  1. Department of Radiology, University of Michigan Health System, C. S. Mott Children’s Hospital, 1500 E. Medical Center Dr., Rm. UH B1-D502, Ann Arbor, MI, 48103, USA

    Ethan A. Smith & Jonathan R. Dillman

  2. Department of Urology, University of Michigan Health System, C. S. Mott Children’s Hospital, 1500 E. Medical Center Dr., Rm. UH B1-D502, Ann Arbor, MI, 48103, USA

    Nicholas Styn & Julian Wan

  3. Department of Pathology, University of Michigan Health System, C. S. Mott Children’s Hospital, 1500 E. Medical Center Dr., Rm. UH B1-D502, Ann Arbor, MI, 48103, USA

    Jonathan McHugh

Authors
  1. Ethan A. Smith
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  2. Nicholas Styn
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  3. Julian Wan
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  4. Jonathan McHugh
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  5. Jonathan R. Dillman
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Corresponding author

Correspondence to Ethan A. Smith.

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Smith, E.A., Styn, N., Wan, J. et al. Xanthogranulomatous pyelonephritis: an uncommon pediatric renal mass. Pediatr Radiol 40, 1421–1425 (2010). https://doi.org/10.1007/s00247-009-1539-4

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  • DOI: https://doi.org/10.1007/s00247-009-1539-4

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