Pediatric Radiology

, Volume 40, Issue 3, pp 361–365 | Cite as

Pulmonary interstitial glycogenosis

  • Michael LanfranchiEmail author
  • Sandra M. Allbery
  • Lisa Wheelock
  • Deborah Perry
Case Report


Although bronchopulmonary dysplasia (BPD) is a common cause of interstitial lung disease in chronically intubated premature neonates, other interstitial lung disease in nonintubated infants is rare. We present a case of pulmonary interstitial glycogenosis that developed in a nonintubated, 31-week gestation infant in whom infectious etiologies had been excluded. The infant was well initially and then developed respiratory distress at 18 days of life. Radiographs at first day of life were normal, but CT and radiographic findings at 18 days of life showed severe interstitial lung disease, mimicking BPD. Lung biopsy showed pulmonary interstitial glycogenosis. This entity is not well described in the pediatric radiology literature and is important to consider, as the condition is responsive to a course of corticosteroids.


Pulmonary interstitial glycogenosis Interstitial lung disease BPD Chest radiograph Neonate 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Michael Lanfranchi
    • 1
    Email author
  • Sandra M. Allbery
    • 2
  • Lisa Wheelock
    • 2
  • Deborah Perry
    • 3
  1. 1.Children’s Hospital & Medical CenterCreighton University Medical SchoolOmahaUSA
  2. 2.Department of RadiologyChildren’s Hospital & Medical CenterOmahaUSA
  3. 3.Department of PathologyChildren’s Hospital & Medical CenterOmahaUSA

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