Abstract
Desmoplastic infantile gangliogliomas (DIGs) are uncommon supratentorial brain tumors with a usually good prognosis despite an aggressive radiological appearance. These tumors form part of a spectrum of desmoplastic infantile tumors that includes desmoplastic infantile astrocytomas. DIGs are classified as benign WHO grade I tumors of infancy. Non-infantile variants of this biologically benign intracranial neoplasm are rare, with only four previous case reports in the literature. We report two cases of non-infantile DIG diagnosed at our institution on the basis of clinical features, radiological appearance and histological findings.
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References
Trehan G, Bruge H, Vinchon M, et al (2004) MR imaging in the diagnosis of desmoplastic infantile tumor: retrospective study of six cases. AJNR 25:1028–1033
Taratuto AL, Monges J, Lylyk P, et al (1984) Superficial cerebral astrocytoma attached to dura: report of six cases in infants. Cancer 54:2505–2512
VandenBerg SR, May EE, Rubinstein LJ, et al (1987) Desmoplastic supratentorial neuroepithelial tumors of infancy with divergent differentiation potential (“desmoplastic infantile gangliogliomas”): report of 11 cases of a distinctive embryonal tumor with favorable prognosis. J Neurosurg 66:58–71
Marti A, Almostarchid B, Maher M, et al (2000) Desmoplastic non-infantile ganglioglioma. Case report. J Neurosurg Sci 44:150–154
Taratuto AL, VandenBerg SR, Rorke LB, et al (2000) Desmoplastic infantile astrocytoma and ganglioglioma. In: Kleihues P, Cavenee WK (eds) Pathology and genetics: tumors of the nervous system. IRC Press, Lyon, France, pp 99–102
Galatioto S, Gullotta F (1996) Desmoplastic non-infantile ganglioglioma. J Neurosurg Sci 40:235–238
Kuchelmeister K, Bergmann M, von Wild K, et al (1993) Desmoplastic ganglioglioma: a report of two non-infantile cases. Acta Neuropathol (Berlin) 85:199–204
Craver RD, Nadell J, Nelson JS, et al (1999) Desmoplastic infantile ganglioglioma. Pediatr Dev Pathol 2:582–587
De Munnynck K, Van Gool S, Van Calenbergh F, et al (2002) Desmoplastic infantile ganglioglioma: a potential malignant tumor? Am J Surg Pathol 26:1515–1522
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In addition to the following list of references, authors are also referred to: Kesavadas C, Sonwalker H, Thomas B, et al. (2005) Atypical MRI appearance of desmoplastic infantile ganglioglioma. Pediatr Radiol 35:1024–1026
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Ganesan, K., Desai, S. & Udwadia-Hegde, A. Non-infantile variant of desmoplastic ganglioglioma: a report of 2 cases. Pediatr Radiol 36, 541–545 (2006). https://doi.org/10.1007/s00247-005-0095-9
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DOI: https://doi.org/10.1007/s00247-005-0095-9