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Gastrointestinal stromal tumour of the duodenum in a 7-year-old boy

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We report a 7-year-old boy presenting with an acute upper gastrointestinal (GI) haemorrhage subsequently diagnosed to have a very rare duodenal gastrointestinal stromal tumour (GIST). Endoscopy, pertechnetate and red cell scans were negative. Abdominal US detected a 17-mm mass lesion of the third part of the duodenum. This was confirmed on CT and shown to be hypervascular on selective angiography. At laparotomy, a 20-mm submucosal duodenal lesion was found associated with mucosal ulceration. Immunohistochemical analysis revealed it to be positive for CD117 (c-KIT protein) consistent with a GIST. We emphasize the importance of a thorough abdominal US examination in children with GI haemorrhage and the consideration of GIST in the diagnosis after the common causes have been excluded.

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We acknowledge the support of Dr. J.M.E. Kirk, Darrent Valley Hospital, Dartford, UK.

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Correspondence to Jacqueline Ann Hughes.

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Hughes, J.A., Cook, J.V., Said, A. et al. Gastrointestinal stromal tumour of the duodenum in a 7-year-old boy. Pediatr Radiol 34, 1024–1027 (2004).

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