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Percutaneous Common Carotid Artery Access for Cardiac Interventions in Infants Does Not Acutely Change Cerebral Perfusion

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Abstract

Pediatric cardiac interventions via percutaneous common carotid artery (CCA) access have been shown to be safe and effective. However, the impact of placement of a sheath in the carotid artery for interventions on cerebral perfusion is unknown. In this study we used cerebral near-infrared spectroscopy (NIRS) to analyze the effects of percutaneous CCA access for cardiac interventions on cerebral perfusion. This study is a retrospective chart review carried out at a tertiary care center on all pediatric patients who underwent percutaneous cardiac catheterization via carotid artery access from January 2010 to January 2020. All patients who had ipsilateral NIRS recorded on the side of carotid artery access were included. Patients with only partial or no ipsilateral NIRS data were excluded. The primary outcome measure was the change in NIRS upon CCA access; the mean NIRS for 15 min before obtaining access was compared to the mean NIRS during the procedure and to the mean NIRS 15 min after removal of the CCA sheath. We hypothesized that there would be a significant drop in NIRS values on the side of CCA access. There were 48 catheterizations in the study period where percutaneous CCA was accessed. Of those, 21 catheterizations had complete data and were included in the study. 13 (62%) were of males. The median age was 23 days (IQR 7–79). The indications for CCA access were patent ductus arteriosus stent implantation (n = 13; 62%), aortic valvuloplasty (n = 5; 24%), balloon angioplasty of coarctation of aorta (n = 2; 10%), and renal artery angioplasty (n = 1; 4%). In 16 patients (72%), the left common carotid artery was accessed. The median weight of the patients was 3.3 kg (IQR 2.8–2.9). The most common sheath size used was 4F, in 16 patients (72%). The mean NIRS prior to the procedure was 67 ± 15%, during the procedure was 68 ± 20%, and after removal of sheath was 68 ± 21%. Paired t test of cerebral NIRS before, during, and after the procedure showed no significant change with CCA access (P = 0.08). No patient in the series had a documented neurologic deficit following the procedure. Percutaneous CCA access was not associated with a decrease in NIRS on the side of the access during the procedure, suggesting there was no significant acute change in cerebral perfusion with CCA access.

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Authors and Affiliations

  1. Department of Pediatric Cardiology, Baylor College of Medicine, Texas Children’s Hospital, 6651 Main Street, E1920, Houston, TX, 77030, USA

    Subhrajit Lahiri, Athar M. Qureshi & Henri Justino

  2. Division of Pediatric Cardiac Anesthesia, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, 77030, USA

    Emad B. Mossad

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  1. Subhrajit Lahiri
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  2. Athar M. Qureshi
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  3. Henri Justino
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  4. Emad B. Mossad
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SL collected the data and wrote the manuscript. AMQ, HJ, and EM contributed significantly on conceptualization and writing the manuscript.

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Correspondence to Subhrajit Lahiri.

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Lahiri, S., Qureshi, A.M., Justino, H. et al. Percutaneous Common Carotid Artery Access for Cardiac Interventions in Infants Does Not Acutely Change Cerebral Perfusion. Pediatr Cardiol 43, 104–109 (2022). https://doi.org/10.1007/s00246-021-02697-9

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  • DOI: https://doi.org/10.1007/s00246-021-02697-9

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