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Multiple Ablation Targets in Children: Multiple Accessory Pathways and Coexistent Arrhythmia

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Abstract

The coexistence of different mechanisms of arrhythmia and multiple accessory pathways (MAPs) leading to multiple ablation targets is rarely seen in children, and data regarding these patients in the literature are limited. Herein, we aimed to evaluate patients who required multiple ablation applications, focusing on different targets during the procedures in children, and evaluating the characteristics of coexistent arrhythmia and MAPs, and the results of these procedures in children. Ablation procedures conducted between March 2009 and December 2018 were evaluated retrospectively, and patients with MAPs and/or coexistent arrhythmia who had undergone ablation procedures were included in the study. Among the 1210 patients who underwent ablation procedures, 52 patients (26 male, 26 female) were ablated for multiple targets. Of the 456 patients with APs, 21 had MAPs (4.6%) and of the 1210 patients who underwent ablation procedures, 31 patients had coexistent arrhythmia (2.5%). The patients had a mean age of 12.24 ± 3.4 (4–18) years and mean body weight of 45.17 ± 14.12 (17–74) kg. A total of 110 APs or foci were identified as quaternary in one patient, while it was triple in four patients. The procedures were unsuccessful in six targets of six patients. Although recurrence was observed in four patients, none were ablated for MAPs. Two complications were encountered, comprising ST segment depression that developed in one patient with Wolf-Parkinson-White syndrome, atrioventricular nodal re-entry tachycardia, and a temporary atrioventricular block during atrioventricular nodal re-entrant tachycardia ablation. The overall success rate according to the pathway/foci number was 94.5% (104/110), with a recurrence rate of 4.5% (5/110), and a complication rate of 1.8% (2/110). The patient success, recurrence, and complication rates were 88.4% (46/52), 7.6% (4/52), and 3.8% (2/52), respectively. In conclusion, the incidence of multiple arrhythmogenic foci and MAPs were not as low as expected in children. A structured and stepwise approach is mandatory for the diagnosis of the different mechanisms of tachycardia, even after successful ablation procedures. The success, recurrence, and complication rates were comparable with those of patients who had a solitary arrhythmogenic focus or solitary AP.

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Data Availability

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

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Funding

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Authors and Affiliations

  1. Division of Pediatric Cardiology, Department of Hacettepe University Faculty of Medicine, Ankara, Turkey

    İlker Ertuğrul, Hayrettin Hakan Aykan & Tevfik Karagöz

  2. Division of Pediatric Cardiology, Dr Sami Ulus Gynecology, Obstetrics and Child Health and Diseases Training and Research Hospital, Ankara, Turkey

    Kutay Sel

  3. Division of Pediatric Cardiology, Department of Dicle University Faculty of Medicine, Diyarbakır, Turkey

    Alper Akın

Authors
  1. İlker Ertuğrul
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  2. Kutay Sel
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  3. Alper Akın
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  4. Hayrettin Hakan Aykan
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Correspondence to Kutay Sel.

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Approval was obtained from the ethics committee of University of Hacettepe. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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Ertuğrul, İ., Sel, K., Akın, A. et al. Multiple Ablation Targets in Children: Multiple Accessory Pathways and Coexistent Arrhythmia. Pediatr Cardiol 42, 1841–1847 (2021). https://doi.org/10.1007/s00246-021-02676-0

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  • DOI: https://doi.org/10.1007/s00246-021-02676-0

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