Pediatric Cardiology

, Volume 38, Issue 7, pp 1405–1409 | Cite as

Single-Center Experience Using Selexipag in a Pediatric Population

  • Roberto Gallotti
  • Diana E. Drogalis-Kim
  • Gary Satou
  • Juan Alejos
Original Article


Pulmonary arterial hypertension (PAH) is a rare and progressive disorder. Current treatment in the pediatric population includes phosphodiesterase 5 inhibitors (PDE-5i), endothelin receptor antagonists (ERA), and both inhaled and intravenous prostacyclin pathway agonists. As of December 22, 2015 the first oral prostacyclin pathway agonist, selexipag (Uptravi®), was FDA approved in the US. In this case series, we discuss our single-center experience using selexipag in a pediatric population, composed of both patients with idiopathic PAH, and patients with congenital heart disease and PAH.


Pediatrics Pulmonary hypertension Remodulin® Selexipag Treprostinil Uptravi® 


Compliance with Ethical Standards

Conflict of interest

Juan Alejos MD has received a speaker honorarium from Actelion Pharmaceuticals.


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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Roberto Gallotti
    • 1
  • Diana E. Drogalis-Kim
    • 1
  • Gary Satou
    • 1
    • 2
  • Juan Alejos
    • 1
    • 2
  1. 1.Department of Pediatric CardiologyMattel Children’s Hospital UCLALos AngelesUSA
  2. 2.Division of Pulmonary HypertensionMattel Children’s Hospital UCLALos AngelesUSA

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