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Chronic Low Dose Prostaglandin and Neonatal Heart Block

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Abstract

Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associated with prolonged prostaglandin E1 (PGE1) infusion. Interestingly, these conduction blocks only occurred at low PGE1 dose. The rhythm disturbances resolved promptly with the discontinuation of PGE1 following surgical repair.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Cardiology, Rush University Medical College, 1653 W. Congress Pkwy., Pavilion 654, Chicago, IL, 60612, USA

    Safwat A. Aly, Sawsan M. Awad, Ra-id Abdulla, Suhaib Kazmouz & Hoang H. Nguyen

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  1. Safwat A. Aly
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  2. Sawsan M. Awad
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  3. Ra-id Abdulla
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  4. Suhaib Kazmouz
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  5. Hoang H. Nguyen
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Correspondence to Safwat A. Aly.

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All the authors declare that they have no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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Aly, S.A., Awad, S.M., Abdulla, Ri. et al. Chronic Low Dose Prostaglandin and Neonatal Heart Block. Pediatr Cardiol 38, 1515–1518 (2017). https://doi.org/10.1007/s00246-017-1633-6

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  • DOI: https://doi.org/10.1007/s00246-017-1633-6

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