Pediatric Cardiology

, Volume 38, Issue 5, pp 893–901 | Cite as

Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis

  • Rohit S. Loomba
  • Matthew W. Buelow
  • Ronald K. Woods
Review Article


It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.


Tetralogy of fallot Repair Timing Neonatal Hypoxia Cyanosis 



No funding was received for this study.

Compliance with Ethical Standards

Conflict of interest

There are no financial disclosures or conflicts of interest for any of the authors.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Rohit S. Loomba
    • 1
  • Matthew W. Buelow
    • 1
  • Ronald K. Woods
    • 1
  1. 1.Division of Cardiology and Cardiothoracic SurgeryChildren’s Hospital of Wisconsin/ Medical College of WisconsinMilwaukeeUSA

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