Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis
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It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.
KeywordsTetralogy of fallot Repair Timing Neonatal Hypoxia Cyanosis
No funding was received for this study.
Compliance with Ethical Standards
Conflict of interest
There are no financial disclosures or conflicts of interest for any of the authors.
- 7.Pigula FA, Khalil PN, Mayer JE, del Nido PJ, Jonas RA (1999) Repair of tetralogy of Fallot in neonates and young infants. Circulation 100: II157–161Google Scholar
- 20.Kirklin J, DuShane J, Patrick R, Donald D, Hetzel P, Harshbarger H, Wood E (1955) Intracardiac surgery with the help of a mechanical pump-oxygenator system (Gibbon type): report of eight cases. Mayo Clin Proc 30:201Google Scholar