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Circulating Progenitor Cells and Childhood Cardiovascular Disease

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Abstract

Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowledge pertaining to circulating progenitor cells in the context of childhood cardiovascular disease. Priorities for further research are also highlighted.

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Acknowledgments

This work was supported by the generosity of the Richard and Helen DeVos Foundation.

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Correspondence to Eric J. Kort.

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Kort, E.J., Croskey, L., Scibienski, T. et al. Circulating Progenitor Cells and Childhood Cardiovascular Disease. Pediatr Cardiol 37, 225–231 (2016). https://doi.org/10.1007/s00246-015-1300-8

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Keywords

  • Congenital heart disease
  • Stem cells
  • Cardiopulmonary bypass
  • Progenitor cells