Pediatric Cardiology

, Volume 37, Issue 2, pp 330–337 | Cite as

Arrhythmias in Adult Congenital Patients With Bodily Isomerism

  • Rohit S. LoombaEmail author
  • Saurabh Aggarwal
  • Navdeep Gupta
  • Matthew Buelow
  • Venkata Alla
  • Rohit R. Arora
  • Robert H. Anderson
Original Article


There are an increasing number of adults with congenital heart disease, some of whom have bodily isomerism. Bodily isomerism or heterotaxy is a unique clinical entity associated with congenital malformations of the heart which further increases the risk for future cardiovascular complications. We aimed to investigate the frequency of arrhythmias in adults with bodily isomerism. We utilized the 2012 iteration of the Nationwide Inpatient Sample to identify adult inpatient admissions associated with arrhythmias in patients with isomerism. Data regarding demographics, comorbidities, and various procedures were collected and compared between those with and without isomerism. A total of 6,907,109 admissions were analyzed with a total of 861 being associated isomerism. The frequency of arrhythmias was greater in those with isomerism (20.8 vs. 15.4 %). Those with isomerism were also more five times more likely to undergo invasive electrophysiology studies. Length and cost of hospitalization for patients with arrhythmias also tended to be greater in those with isomerism. Mortality did not differ between the two groups. Arrhythmias are more prevalent in those with isomerism, with a majority of arrhythmias in isomerism being atrial. Those with isomerism and arrhythmias also tended to have greater length and cost of hospitalization.


Arrhythmias Isomerism Heterotaxy Atrioventricular block Supraventricular tachycardia Conduction 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Rohit S. Loomba
    • 1
    Email author
  • Saurabh Aggarwal
    • 2
  • Navdeep Gupta
    • 1
  • Matthew Buelow
    • 1
  • Venkata Alla
    • 2
  • Rohit R. Arora
    • 3
  • Robert H. Anderson
    • 4
  1. 1.Medical College of WisconsinMilwaukeeUSA
  2. 2.Creighton University Medical CenterOmahaUSA
  3. 3.Chicago Medical SchoolNorth ChicagoUSA
  4. 4.Institute of Genetic MedicineNewcastle UniversityNewcastle upon TyneUK

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