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Factors Associated With the Occurrence and Treatment of Supraventricular Tachycardia in a Pediatric Congenital Heart Disease Cohort

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Abstract

In patients with congenital heart disease (CHD), the association between supraventricular tachycardia (SVT), type of pathophysiology, and therapeutic interventions in a population-based cohort warrants further examination. A retrospective, longitudinal 15-year data set (1996–2010) was analyzed. Inclusion criteria included age ≤17 years, enrolled in South Carolina State Medicaid, and diagnosed as having one or more CHDs as well as SVT. SVT was diagnosed in 6.5 % of CHD patients (N = 1,169) during the 15-year epoch investigated. SVT was less likely to occur in African-American (hazard ratio [HR] = 0.76) or male patients (HR = 0.88), but it was significantly more likely to occur in patients age ≤12 months or in adolescents ≥13 years in those undergoing multiple surgeries/medical interventions for their CHD (HR = 1.14), those receiving antiarrhythmic/diuretic/preload-/afterload-reducing medications (HR = 5.46), and those with severe/cyanotic CHDs (HR = 1.52) or chromosomal abnormalities (HR = 1.64). Children who had an atrial septal defect secundum (adjusted odds ratio [aOR] = 3.03) and those treated with diuretic or antiarrhythmic medication (aOR = 1.80) were significantly more likely to undergo SVT ablation, whereas those with late-onset pulmonary hypertension (ages 6–12 years old) were significantly less likely to undergo SVT ablation. SVT recurred in only 14 of 166 patients who underwent SVT ablation. Multiple medical interventions at an early age may increase the risk of SVT occurrence in young CHD patients regardless of the severity/complexity of the CHD.

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References

  1. Anand RG, Rosenthal GL, Van Hare GF, Snyder CS (2009) Is the mechanism of supraventricular tachycardia in pediatrics influenced by age, gender or ethnicity? Congenit Heart Dis 4(6):464–468

    Article  PubMed  Google Scholar 

  2. Bernstein D (2011). Epidemiology and genetic basis of congenital heart disease. In: RM Kliegman et al. (eds.), Nelson Textbook of Pediatrics, 19th edn. Saunders, Philadelphia, Available at: http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4377-0755-7.00418-8-s0015&isbn=978-1-4377-0755-7&sid=1430184210&uniqId=408661955-3#4-u1.0-B978-1-4377-0755-7.00418-8-s0015. Accessed 23 Jan 2013

  3. Botto LD, Correa A, Erickson JD (2001) Racial and temporal variations in the prevalence of heart defects. Pediatrics 107(3):E32

    Article  CAS  PubMed  Google Scholar 

  4. Buddhe S, Singh H, Du W, Karpawich PP (2012) Radiofrequency and cryoablation therapies for supraventricular arrhythmias in the young: five-year review of efficacies. Pacing Clin Electrophysiol 35(6):711–717

    Article  PubMed  Google Scholar 

  5. Calabrò MP, Cerrito M, Luzza F, Oreto G (2008) Supraventricular tachycardia in infants: Epidemiology and clinical management. Curr Pharm Des 14(8):723–728

    Article  PubMed  Google Scholar 

  6. Census 2010, summary file 2, demographic profile 1 by state. Available at http://factfinder2.census.gov/faces/tableservices/jsf/pages/productview.xhtml?pid=DEC_10_SF2_SF2DP1&prodType=table. Accessed 4 Feb 2013

  7. Chang PM, Silka MJ, Moromisato DY, Bar-Cohen Y (2010) Amiodarone versus procainamide for the acute treatment of recurrent supraventricular tachycardia in pediatric patients. Circ Arrhythm Electrophysiol 3(2):134–140

    Article  CAS  PubMed  Google Scholar 

  8. Children under 18 [Table D1] and their designated parents and children under 18 and their designated parents [Table D2]—Characteristics of families (including region). Available at http://www.census.gov/hhes/socdemo/children/data/sipp/well2009/tables.html. Accessed 30 Jan 2013

  9. Chiu SN, Lu CW, Chang CW, Chang CC, Lin MT, Lin JL et al (2009) Radiofrequency catheter ablation of supraventricular tachycardia in infants and toddlers. Circ J 73(9):1717–1721

    Article  PubMed  Google Scholar 

  10. De Santis A, Fazio G, Silvetti MS, Drago F (2008) Transcatheter ablation of supraventricular tachycardias in pediatric patients. Curr Pharm Des 14(8):788–793

    Article  PubMed  Google Scholar 

  11. Dilber E, Mutlu M, Dilber B, Aslan Y, Gedik Y, Celiker A (2010) Intravenous amiodarone used alone or in combination with digoxin for life-threatening supraventricular tachyarrhythmia in neonates and small infants. Pediatr Emerg Care 26(2):82–84

    Article  PubMed  Google Scholar 

  12. Hafez M, Abu-Elkheir M, Shokier M, Al-Marsafawy H, Abo-Haded H, El-Maaty MA (2012) Radiofrequency catheter ablation in children with supraventricular tachycardias: intermediate term follow up results. Clin Med Insights Cardiol 6:7–16

    Article  PubMed Central  PubMed  Google Scholar 

  13. Health insurance coverage for children under 19 years of age, at or below 200 % of poverty by state, 2006–2008 and 2009–2011. Available at http://www.census.gov/hhes/www/hlthins/data/children/low-income.html. Accessed 30 Jan 2013

  14. Hoffman JI, Kaplan S (2002) The incidence of congenital heart disease. J Am Coll Cardiol 39(12):1890–1900

    Article  PubMed  Google Scholar 

  15. Inaba AS, Horeczko T (2009) Cardiac disorders. In: Marx JA, Hockberger RS, Walls RM, et al (eds.) Rosen’s Emergency Medicine. 7th ed. Pa: Mosby Elsevier, Philadelphia chap 166 Available at: http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05472-0.00169-9-s0110&isbn=978-0-323-05472-0&sid=1423407102&uniqId=406675227-4#4-u1.0-B978-0-323-05472-0.00169-9-s0295. Accessed 30 Jan 2013

  16. Kanter RJ (2010) Pearls for ablation in congenital heart disease. J Cardiovasc Electrophysiol 21:223–230

    Article  PubMed  Google Scholar 

  17. Karpawich PP, Pettersen MD, Gupta P, Shah N (2008) Infants and children with tachycardia: Natural history and drug administration. Curr Pharm Des 14(8):743–752

    Article  CAS  PubMed  Google Scholar 

  18. Knudson JD, Cannon BC, Kim JJ, Moffett BS (2011) High-dose sotalol is safe and effective in neonates and infants with refractory supraventricular tachyarrhythmias. Pediatr Cardiol 32(7):896–903

    Article  PubMed  Google Scholar 

  19. Salerno JC, Garrison MM, Larison C, Seslar SP (2011) Case fatality in children with supraventricular tachycardia in the United States. Pacing Clin Electrophysiol 34(7):832–836

    Article  PubMed  Google Scholar 

  20. Sanatani S, Potts JE, Reed JH, Saul JP, Stephenson EA, Gibbs KA et al (2012) The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. Circ Arrhythm Electrophysiol 5(5):984–991

    Article  CAS  PubMed  Google Scholar 

  21. Sulafa Ali KM (2008) Collateral effects of antiarrhythmics in pediatric age. Curr Pharm Des 14(8):782–787

    Article  Google Scholar 

  22. Vignati G, Annoni G (2008) Characterization of supraventricular tachycardia in infants: Clinical and instrumental diagnosis. Curr Pharm Des 14(8):729–735

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

Funding for this study was provided through a Clinical Incentive Research Grant from the University of South Carolina, Office of the Provost. No external funding was received.

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Authors and Affiliations

  1. Department Medicine, University of Mississippi School of Medicine, 2500 N State St, Jackson, MS, 39216, USA

    Avnish Tripathi

  2. Department of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, SC, 29203, USA

    Yong-Moon Mark Park

  3. Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, 15 Medical Park, Suite 301, Columbia, SC, 29203, USA

    George B. Black & Jeanette M. Jerrell

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  1. Avnish Tripathi
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  2. George B. Black
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  3. Yong-Moon Mark Park
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  4. Jeanette M. Jerrell
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Correspondence to Jeanette M. Jerrell.

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Tripathi, A., Black, G.B., Park, YM.M. et al. Factors Associated With the Occurrence and Treatment of Supraventricular Tachycardia in a Pediatric Congenital Heart Disease Cohort. Pediatr Cardiol 35, 368–373 (2014). https://doi.org/10.1007/s00246-013-0784-3

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  • DOI: https://doi.org/10.1007/s00246-013-0784-3

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