Skip to main content
Log in

Cardiac Tumors in Infants and Children: Study of 120 Operated Patients

  • Original Article
  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

Abstract

Cardiac tumors in children are rare, and patient series are limited in size. We report 120 children who underwent surgery to treat a cardiac tumor; the tumor type was known in 108 instances. The patients represented <0.1 % of 130,000 cardiac surgeries performed in children from a multi-institutional data base. The most common tumors and the number of patients were rhabdomyoma (n = 42), myxoma (n = 28), and fibromas (n = 10). The remaining 18 tumors of various types occurred in smaller numbers of patients. Nine patients (7 %) died after surgery. The mean age of death was 14 days, and death was most frequent in patients with fibromas (n = 4). Considering the variety of tumors, their varied location in cardiac structures, the patient ages, and the infrequent occurrence in an individual surgeon’s experience, the operative mortality was low.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Becker AE (2000) Primary heart tumors in the pediatric age group: A review of salient pathologic features relevant for clinicians. Pediatr Cardiol 21:317–323

    Article  PubMed  CAS  Google Scholar 

  2. Beghetti M, Gow RM, Haney I, Mawson J, Williams WG, Freedom RM (1997) Pediatric primary benign cardiac tumors: a 15-year review. Am Heart J 134:1107–1114

    Article  PubMed  CAS  Google Scholar 

  3. Black MD, Kadletz M, Smallhorn JF, Freedom RM (1998) Cardiac rhabdomyomas and obstructive left heart disease: histologically but not functionally benign. Ann Thorac Surg 65:1388–1390

    Article  PubMed  CAS  Google Scholar 

  4. Burke AP, Cowan D, Virmani R (1992) Primary sarcomas of the heart. Cancer 69:387–395

    Article  PubMed  CAS  Google Scholar 

  5. Centofanti P, Di Rosa E, Deorsola L, Dato GM et al (1999) Primary cardiac tumors: early and late results of surgical treatment in 91 patients. Ann Thorac Surg 68:1236–1241

    Article  PubMed  CAS  Google Scholar 

  6. Chao AS, Chao A, Wang TH, Change YC et al (2008) Outcome of antenatally diagnosed cardiac rhabdomyoma: case series and a meta-analysis. Ultrasound Obstet Gynecol 31:289–295

    Article  PubMed  CAS  Google Scholar 

  7. Edwards A, Bermudez C, Piwonka G, Berr ML et al (2002) Carney’s syndrome: complex myxomas. Report of four cases and review of the literature. Cardiovasc Surg 10:264–275

    Article  PubMed  CAS  Google Scholar 

  8. Freedom RM, Lee KJ, MacDonald C, Taylor G (2000) Selected aspects of cardiac tumors in infancy and childhood. Pediatr Cardiol 21:299–316

    Article  PubMed  CAS  Google Scholar 

  9. Ganame J, D’hooge J, Mertens L (2005) Different deformation patterns in intracardiac tumors. Eur J Echocardiogr 6:641–644

    Article  Google Scholar 

  10. Gazit AZ, Singh GK, Shumway J, Johnson MC, Ludomirsky A (2007) Fetal cardiac rhabdomyoma: A sheep or a wolf? J Matern Fetal Neonatal Med 20:343–848

    Article  PubMed  Google Scholar 

  11. Geipel A, Krapp M, Germer U, Becker R, Gembruch U (2001) Perinatal diagnosis of cardiac tumors. Ultrasound Obstet Gynecol 17:17–21

    Article  PubMed  CAS  Google Scholar 

  12. Goldberg SP, Boston US, Turpin DA, Mari GC et al (2010) Surgical management of intrapericardial teratoma in the fetus. J Pediatr 156:848–849

    Article  PubMed  Google Scholar 

  13. Gunther T, Schreiber C, Noebauer C, Eicken A, Lange R (2008) Treatment strategies for pediatric patients with primary cardiac and pericardial tumors: a 30-year review. Pediatr Cardiol 29:1071–1076

    Article  PubMed  Google Scholar 

  14. Holley DG, Martin GR, Brenner JI, Fyfe DA et al (1995) Diagnosis and management of fetal cardiac tumors: a multicenter experience and review of published reports. J Am Coll Cardiol 26:516–520

    Article  PubMed  CAS  Google Scholar 

  15. Isaacs H Jr (2004) Fetal and neonatal cardiac tumors. Pediatr Cardiol 25:252–273

    Article  PubMed  Google Scholar 

  16. Lacey SR, Donofrio MT (2007) Fetal cardiac tumors: prenatal diagnosis and outcome. Pediatr Cardiol 28:61–67

    Article  PubMed  CAS  Google Scholar 

  17. Nir A, Tajik AJ, Freeman WK, Seward JB et al (1995) Tuberous sclerosis and cardiac rhabdomyoma. Am J Cardiol 76:419–421

    Article  PubMed  CAS  Google Scholar 

  18. Reardon MJ, Malaisrie SC, Walkes JC, Vaporciyan AA et al (2006) Cardiac autotransplantation for primary cardiac tumors. Ann Thorac Surg 82:645–650

    Article  PubMed  Google Scholar 

  19. Stiller B, Hetzer R, Meyer R, Dittrich S et al (2001) Primary cardiac tumours: when is surgery necessary? Eur J Cardiothorac Surg 20:1002–1006

    Article  PubMed  CAS  Google Scholar 

  20. Thomas-de-Montpreville V, Nottin R, Dulmet E, Serraf A (2007) Heart tumors in children and adults: clinicopathological study of 59 patients from a surgical center. Cardiovasc Pathol 16:22–28

    Article  PubMed  Google Scholar 

  21. Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV (2007) Cardiac tumours in children. Orphanet J Rare Dis 2:11

    Article  PubMed  Google Scholar 

  22. Wu KH, Mo XM, Liu YL (2009) Clinical analysis and surgical results of cardiac myxoma in pediatric patients. J Surg Oncol 99:48–50

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to James H. Moller.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bielefeld, K.J., Moller, J.H. Cardiac Tumors in Infants and Children: Study of 120 Operated Patients. Pediatr Cardiol 34, 125–128 (2013). https://doi.org/10.1007/s00246-012-0399-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00246-012-0399-0

Keywords

Navigation