Abstract
Therapy-refractory supraventricular tachycardias commonly result in hydrops and death in human fetuses. Fetal transesophageal electrocardiography may aid in understanding its underlying electrophysiological mechanism and allow stimulation. Percutaneous fetoscopic deployment of an electrode catheter into the fetal esophagus by way of a single trocar was performed in a human fetus and permitted the recording of a fetal transesophageal electrocardiogram at 35 + 6 weeks of gestation. Fetal transesophageal electrocardiography can be achieved in human fetuses by way of a minimally invasive percutaneous fetoscopic approach and carries the potential to improve diagnosis and management of therapy-refractory supraventricular tachycardias in human fetuses.
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Kohl T, Kirchhof P, Gogarten W, Asfour B, Haverkamp W, Reckers J et al (1999) Fetal transesophageal electrocardiography and stimulation in sheep―Fetoscopic techniques aimed at diagnosis and therapy of incessant fetal tachycardias. Circulation 100:772–776
Kohl T, Große Hartlage N, Kienitz D, Westphal M, Brentrup A, Aryee S et al (2003) Percutaneous fetoscopic tracheal balloon occlusion in sheep—a minimally invasive approach aimed at reduction of maternal injury during fetal surgery for diaphragmatic hernia. Surg Endosc 17:1454–1460
Kohl T, Hering R, Van de Vondel P, Tchatcheva K, Berg C, Bartmann P et al (2006) Analysis of the step-wise clinical introduction of experimental percutaneous fetoscopic surgical techniques for upcoming minimally-invasive fetal cardiac interventions. Surg Endosc 20:1134–1143
Srinivasan S, Strasburger J (2008) Overview of fetal arrhythmias. Curr Opin Pediatr 20:522–531
Acknowledgments
We acknowledge the support of Monika Butz in documenting the procedure. The development of percutaneous fetoscopic techniques for fetal cardiac interventions has been supported by educational and research grants (Grants Nos. Ko 1484/1-1, Ko 1484/2-1, Ko 1484/3-1, Ko 1484/3-2, and Ko 1484/3-3) from the Deutsche Forschungsgemeinschaft, Bonn, Germany.
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Kohl, T., Herberg, U. Fetoscopic Fetal Transesophageal Electrocardiography: A Minimally Invasive Tool for Cardiac Monitoring, Diagnostics, and Intervention in Human Fetuses. Pediatr Cardiol 31, 717–719 (2010). https://doi.org/10.1007/s00246-010-9658-0
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DOI: https://doi.org/10.1007/s00246-010-9658-0