Abstract
Patients with systemic lupus erythematosus (SLE) may present with acute coronary syndrome (ACS) due to coronary vasculitis or premature atherosclerosis. There is a paucity of data on invasive management strategies for young adults who present with an ACS secondary to active vasculitis. This article describes the case of a teenager who presented with an ACS secondary to lupus vasculitis as his first presentation of active SLE. Coronary angiography showed a left main equivalent lesion involving a proximal very large left anterior descending artery (LAD) and diagonal stenosis (with a diminutive left circumflex artery). The boy underwent a successful endoscopic coronary bypass surgery to his LAD followed by percutaneous coronary intervention to his diagonal artery. This case demonstrates the feasibility and safety of a hybrid coronary revascularization in a teenager with acute coronary syndrome due to coronary vasculitis.
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References
Aldoboni AH, Hamza EA, Majdi K, et al. (2002) Spontaneous dissection of coronary artery treated by primary stenting as the first presentation of systemic lupus erythematosus. J Invasive Cardiol 14:694–696
Dropinski J, Szczeklik W, Rubis P (2003) Cardiac involvement in systemic autoimmune disease. Pol Arch Med Wewn 109:375–381
Ginzler EM, Schorn K (1988) Outcome and prognosis in systemic lupus erythematosus. Rheum Dis Clin North Am 14:67–78
Haider YS, Roberts WC (1981) Coronary arterial disease in systemic lupus erythematosus: Quantification of degrees of narrowing in 22 necropsy patients (21 women) aged 16 to 37 years. Am J Med 70:775–781
Karrar A, Sequeira W, Block JA (2001) Coronary artery disease in systemic lupus erythematosus: A review of the literature. Semin Arthritis Rheum 30:436–443
Lagerqvist B, James SK, Stenestrand U, et al. (2007) Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden. N Engl J Med 356:1009–1019
Leclerc KM, Mascette AM, Schachter DT, Wicks AB (1999) Spontaneous coronary artery dissection in a young woman treated with extensive coronary stenting. J Invasive Cardiol 11:237–241
Mandell BF (1987) Cardiovascular involvement in systemic lupus erythematosus. Semin Arthritis Rheum 17:126–141
Manzi S, Selzer F, Sutton-Tyrrell K, et al. (1999) Prevalence and risk factors of carotid plaque in women with systemic lupus erythematosus. Arthritis Rheum 42:51–60
Nanke Y, Kotake S, Shimamoto K, et al. (2000) Systemic lupus erythematosus with myocardial dysfunction due to microvasculopathy. Lupus 9:464–467
Sella EM, Sato EI, Leite WA, et al. (2003) Myocardial perfusion scintigraphy and coronary disease risk factors in systemic lupus erythematosus. Ann Rheum Dis 62:1066–1070
Spaulding C, Daemen J, Boersma E, et al. (2007) A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents. N Engl J Med 356:989–997
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Mehta, P.K., Samady, H., Vassiliades, T.A. et al. Acute Coronary Syndrome as a First Presentation of Systemic Lupus Erythematosus in a Teenager: Revascularization by Hybrid Coronary Artery Bypass Graft Surgery and Percutaneous Coronary Intervention: Case Report. Pediatr Cardiol 29, 957–961 (2008). https://doi.org/10.1007/s00246-007-9157-0
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DOI: https://doi.org/10.1007/s00246-007-9157-0