Abstract
We present a case of nearly total posterior mitral leaflet destruction due to Loeffler endocarditis associated with Hodgkin’s lymphoma in a 15-year-old adolescent. The patient was treated medically with subsequent surgical mitral valve replacement. Cardiac aspects of hypereosinophilic syndrome are also discussed.
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Ascione L, De Michele M, Accadia M, Spadaro P, Rumolo S, Tuccillo B (2004) Reversal of cardiac abnormalities in a young man with idiopathic hypereosinophilic syndrome using a tyrosine kinase inhibitor. Eur J Echocardiogr 5(5):386–390
Benezet-Mazuecos J, de la Fuente A, Marcos-Alberca P, Farre J (2007) Loeffler endocarditis: what have we learned? Am J Hematol 82(10):861–862
Endo M, Usuki K, Kitazume K, Iwabe K, Okuyama Y, Urabe A (1995) Hypereosinophilic syndrome in Hodgkin’s disease with increased granulocyte-macrophage colony-stimulating factor. Ann Hematol 71(6):313–314
Fletcher S, Bain B (2007) Diagnosis and treatment of hypereosinophilic syndromes. Curr Opin Hematol 14(1):37–42
Fuzellier JF, Chapoutot L, Torossian PF, Metz D, Baehrel B (2005) Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. J Cardiac Surg 20(5):472–474
Hayashi S, Isobe M, Okubo Y, Suzuki J, Yazaki Y, Sekiguchi M (1999) Improvement of eosinophilic heart disease after steroid therapy: successful demonstration by endomyocardial biopsied specimens. Heart Vessels 14(2):104–108
Hii MW, Firkin FC, MacIsaac AI, Yii M (2006) Obstructive prosthetic mitral valve thrombosis in idiopathic hypereosinophilic syndrome: a case report and review of the literature. J Heart Valve Dis 15(5):721–725
Mendes De Leon DE (1976) Eosinophilic leukaemia, Hodgkin’s disease and Loeffler-type fibroplastic parietal endocarditis. Neth J Med 19(3):148–155
Patchell R, Perry MC (1981). Eosinophilic meningitis in Hodgkin disease. Neurology 31(7):887–888
Pinto A, Aldinucci D, Gloghini A, et al. (1997) The role of eosinophils in the pathobiology of Hodgkin’s disease. Ann Oncol 8(Suppl 2):89–96
Tanaka H, Kawai H, Tatsumi K, et al. (2006) Surgical treatment for Löffler’s endocarditis with left ventricular thrombus and severe mitral regurgitation: a case report. J Cardiol 47(4):207–213
Vassallo C, Ciocca O, Arcaini L, Brazzelli V, Ardigò M, Lazzarino M, Borroni G (2002) Eosinophilic folliculitis occurring in a patient affected by Hodgkin lymphoma. Int J Dermatol 41(5):298–300
Watanabe K, Tournilhac O, Camilleri LF (2002) Recurrent thrombosis of prosthetic mitral valve in idiopathic hypereosinophilic syndrome. J Heart Valve Dis 11(3):447–449
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Yalonetsky, S., Mishaly, D., Ben-Barak, A. et al. Mitral Valve Destruction by Hodgkin’s Lymphoma-Associated Loefler Endocarditis. Pediatr Cardiol 29, 983–985 (2008). https://doi.org/10.1007/s00246-007-9135-6
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DOI: https://doi.org/10.1007/s00246-007-9135-6