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Cribriform Amplatzer Device Closure of Fenestrated Atrial Septal Defects: Feasibility and Technical Aspects

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Abstract

Fenestrated atrial septal defects (F-ASDs) may pose a challenge to device closure; recently, a cribriform device with a minimal connecting intrawaist diameter and large, equal left- and right-sided discs has been designed to cover more than one adjacent defect. This study demonstrates the feasibility and technical aspects of closing F-ASDs using this new device. Sixteen patients between August 2003 and January 2006 were included in this study. The inclusion criterion was the presence of a F-ASD diagnosed by transesophageal echocardiography. One of the three available cribriform ASD device sizes (18, 25, or 35 mm) was implanted. Patients were followed for at least 1 year after the procedure. Thirteen patients had successful cribriform ASD device implantation (median age and weight, 12.5 years and 36 kg, respectively). Ten patients (62%) had an associated atrial septal aneurysm. The mean procedure time was 75.6 ± 28.5 min and the mean fluoroscopy time 14.8 ± 6.3 min. The RVEDD was significantly reduced, from a mean of 24.2 mm to 21.0 (p < 0.05). One patient developed atrial tachycardia requiring cardioversion during the procedure. There were no embolic events, heart block, or mortality. Complete closure was 10 of 13 (77 %) the next day and 12 of 13 (92%) at 6 and 12 months. We conclude that the cribriform Amplatzer device can be successfully and safely used in patients with F-ASDs. Complete closure may take up to 6 months.

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Authors and Affiliations

  1. Hamad Medical Corporation, Doha, Qatar

    Mohammed Numan, Amal El Sisi, Salwa Gendi, Tohami Tohami & Howaida G. El-Said

  2. Glenfield Hospital, Leicester, UK

    Magdi Tofeig

  3. MD 3020 Children’s Way, MC-5004, San Diego, 92123, California, USA

    Howaida G. El-Said

  4. Cairo University, Cairo, Egypt

    Howaida G. El-Said

Authors
  1. Mohammed Numan
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  2. Amal El Sisi
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  3. Magdi Tofeig
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  4. Salwa Gendi
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  5. Tohami Tohami
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  6. Howaida G. El-Said
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Correspondence to Howaida G. El-Said.

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Numan, M., El Sisi, A., Tofeig, M. et al. Cribriform Amplatzer Device Closure of Fenestrated Atrial Septal Defects: Feasibility and Technical Aspects. Pediatr Cardiol 29, 530–535 (2008). https://doi.org/10.1007/s00246-007-9079-x

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  • DOI: https://doi.org/10.1007/s00246-007-9079-x

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