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Bidirectional Cavopulmonary Anastomosis: Impact on Diastolic Ventricular Function Indices

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Abstract

Systolic ventricular function has been demonstrated to remain unchanged following bidirectional cavopulmonary anastomosis (BCPA). The effects of BCPA on diastolic ventricular performance have not been critically assessed. The objective of this study was to evaluate the changes in diastolic ventricular function indices early after BCPA. Nineteen patients were enrolled prospectively. Transthoracic echocardiograms were performed at a median of 4 days prior to and 5 days subsequent to BCPA. Diastolic and systolic echocardiographic indices of ventricular performance were measured for the dominant ventricle. End diastolic volume decreased postoperatively (71.1 ± 21.1 vs 68.08 ± 17.9 ml/m2, p = 0.05). Tei index increased postoperatively (0.51 ± 0.2 vs 0.62 ± 0.1, p = 0.002), whereas inflow Doppler E velocity (70.3 ± 13 vs 56.3 ± 24.7 cm/sec, p = 0.04), E/A ratio (1.18 ± 0.52 vs 0.84 ± 0.2, p = 0.02), tissue Doppler E′ velocity (9.5 ± 2.5 vs 6.4 ± 3.2 cm/sec, p = 0.03) and diastolic flow propagation velocity (56.5 ± 12 vs 52.8 ± 11 cm/sec, p = 0.04) all decreased. There was no change in ventricular mass, area change fraction, heart rate, or inflow Doppler A or tissue Doppler A′ and S′ velocities. This study demonstrated that diastolic indices of ventricular performance are altered indicating decreased diastolic function early following BCPA. Whether this observation is a result of a change in ventricular mass:volume ratio, loading conditions of the ventricle, ventricular geometry, or the effects of cardiopulmonary bypass remains to be determined.

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Notes

  1. The difference between the bidirectional Glenn procedure and hemi-Fontan procedure is that in the hemi-Fontan procedure a connection between the right atrial–superior vena cava junction and the pulmonary arteries is established.

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Authors and Affiliations

  1. Division of Pediatric Cardiology, Morgan Stanley Children’s Hospital of New York Presbyterian, Columbia University, College of Physicians & Surgeons, New York, NY, USA

    E. S. Selamet Tierney, J. S. Glickstein, K. Altmann, D. E. Solowiejczyk, R. S. Mosca, J. M. Quaegebeur, C. S. Kleinman & B. F. Printz

  2. Department of Cardiology, Children’s Hospital Boston, Farley 2, 300 Longwood Avenue, Boston, MA, 02155, USA

    E. S. Selamet Tierney

Authors
  1. E. S. Selamet Tierney
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  2. J. S. Glickstein
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  3. K. Altmann
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  4. D. E. Solowiejczyk
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  5. R. S. Mosca
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  6. J. M. Quaegebeur
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  7. C. S. Kleinman
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  8. B. F. Printz
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Correspondence to E. S. Selamet Tierney.

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Tierney, E.S.S., Glickstein, J.S., Altmann, K. et al. Bidirectional Cavopulmonary Anastomosis: Impact on Diastolic Ventricular Function Indices. Pediatr Cardiol 28, 372–378 (2007). https://doi.org/10.1007/s00246-006-0122-0

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  • DOI: https://doi.org/10.1007/s00246-006-0122-0

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