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Two Young Adults Who Had Acute Coronary Syndrome after Regression of Coronary Aneurysms Caused by Kawasaki Disease in Infancy

Pediatric Cardiology volume 27, pages 372–375 (2006)Cite this article

Abstract

We report two young adult patients who had acute coronary syndrome after regression of coronary aneurysms caused by Kawasaki disease (KD). A 26 year-old man had acute anterior myocardial infarction at midnight after drinking alcohol. He had had bilateral coronary aneurysms caused by KD at the age of 8 months. Selective coronary angiograms (CAGs) at the age of 7 years revealed regression of both coronary aneurysms. He had no symptoms until the onset of acute myocardial infarction. The other patient was a 24 year-old man diagnosed as having a subendocardial infarction. He had had bilateral coronary aneurysms caused by KD at the age of 1 year. CAGs at the age of 9 years showed that both had regressed. It should be recognized that young adults with apparently normal coronary arteries angiographically after regression of large coronary aneurysms caused by KD may occasionally have acute coronary syndromes. We suspect intimal involvement of the coronary arterial wall after regression of the large aneurysms underlies the acute coronary syndrome in adults. Risk factors for atherosclerosis must be avoided in this population.

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Acknowledgments

We thank Professor Peter Olley and Dr. Setsuko Olley for their English language consultation. We thank Dr. Teiji Akagi (Kurume University) and Dr. Kenji Kishida (Kokura Memorial Hospital) for their cooperation.

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Affiliations

  1. Department of Pediatrics, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, Osaka, 565-8565, Japan

    E. Tsuda, K. Kurosaki & S. Echigo

  2. Department of Cardiovascular Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, Osaka, 565-8565, Japan

    A. Hanatani

  3. Department of Radiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, Osaka, 565-8565, Japan

    H. Naito

Authors
  1. E. Tsuda
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  2. A. Hanatani
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  3. K. Kurosaki
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  4. H. Naito
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  5. S. Echigo
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Correspondence to E. Tsuda.

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Tsuda, E., Hanatani, A., Kurosaki, K. et al. Two Young Adults Who Had Acute Coronary Syndrome after Regression of Coronary Aneurysms Caused by Kawasaki Disease in Infancy. Pediatr Cardiol 27, 372–375 (2006). https://doi.org/10.1007/s00246-005-1233-8

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  • DOI: https://doi.org/10.1007/s00246-005-1233-8

Keywords

  • Kawasaki disease
  • Coronary artery aneurysm
  • Acute myocardial infarction